The free vintage image of files for today’s header image is courtesy of iStock and Google Images.
Health Friday is a series devoted to Big Pharma, vaccines, general health, and associated topics. As today’s offering speaks to the disaster of COVID-19, Yours Truly dedicates it to all persons, of whatever age or location, who have suffered injuries, illnesses, or disabilities; or, who have passed away from, the manifestations of the COVID-19 disaster: from an infection of the COVID-19 virus itself; or, from COVID-19 “vaccine”-induced or -aggravated injuries, illnesses, or disabilities due to the COVID-19 “vaccines” that they took; or, from complications induced by the shedding of either the COVID-19 virus itself, or by the COVID-19 “vaccines.”
There are Important Notifications by our host, Wolf Moon; the Rules of out late, good Wheatie; and, certain caveats from Yours Truly, of which readers should be aware. They are linked here. Note: Yours Truly has checked today’s offering for AI-generated content; to the best of her knowledge and belief, there is none, except perhaps for AI-generated images within linked URLs. If readers wish to post AI-generated content to today’s discussion thread, they must cite their source. Thank you.
Special Note regarding today’s offering: In no way is the following, or The Baric Files series in general in Health Friday posts, to be construed as a “character assassination”, or as an “indictment”, or as any other type of attack or smear on Ralph S. Baric, PhD, of the UNC Gillings School of Global Public Health of the University of North Carolina, Chapel Hill, or of his lab at the university. The linked scientific papers, images therefrom, and other information about Dr. Baric (such as, his Curriculum Vitae) are all available on the internet. The ideas and conclusions of today’s offering are by Yours Truly. There is a plethora of items related to Dr. Baric; Yours Truly will focus on some of them in each part of The Baric Files.
Today’s offering is Part Two of four. Please refer to Part One for previous information: https://www.theqtree.com/2025/12/05/health-friday-12-5-2025-open-thread-the-baric-files-part-one/.
Now, to today’s offering:The Baric Files, Part Two: Of Mice, Rabbits, Templates, and AI 23946 (also known as AI023946 as per NIH Reporter.)
In reading through the section VIII. PUBLISHED MANUSCRIPTS: in the Curriculum Vitae for Ralph S. Baric, PhD, of the UNC Gillings School of Global Public Health at the University of North Carolina, Chapel Hill, it appears that Dr. Baric’s research efforts began to shift away from the Sindbis virus that he was investigating early on in his career, to murine (mice), rabbits, and coronaviruses in general: for example, published manuscripts starting with number 11. Please see the screenshot, below, of portions of Page 11 and Page 12 of his Curriculum Vitae [1]:

Yours Truly turns to published manuscript number 11, dated 1986. By now in the research journey of Dr. Baric, it appears that he was starting to experiment with combining pieces of viruses, a process called “recombination.” Published manuscript number 11 [2] is the result of such experiments with mouse coronaviruses. At the time that this paper was published, Dr. Baric was a Post-doctoral Fellow at the University of Southern California Los Angeles School of Medicine. This occurred before he was hired by the University of North Carolina Chapel Hill. Please see the screenshots from this paper, below; first, the general summary; and, second, a portion of the Discussion section:


Note the mentions of “mRNAs”, “coronavirus”, “transcription”, and “recombinant viruses.”
There are other published manuscripts (papers) by Dr. Baric that relate to experiments with mouse coronaviruses, such paper number 16, from 1988, which discusses the interaction between certain coronavirus sequences and “the nucleocapsid protein” [3].
By the year 1990, Dr. Baric’s research journey had led to studying heart issues in rabbits. The first result of this study was the 1990 paper, “Rabbit cardiomyopathy” [4]. Please see the screenshots of the Title page of this paper; the Introduction of this paper; and, a portion of the Discussion section, below:



There is one more screenshot from this 1990 paper, which Yours Truly considers to be a significant publication in the research journey of Dr. Baric: the Acknowledgements section:

Please take note of the mention of NIH grant AI 23946. This grant also funded, for example:
The 1992 paper by Dr. Baric and colleagues, “An experimental model for dilated cardiomyopathy after rabbit coronavirus infection” [5}. Please see the screenshots from this paper, below: the Title and general summary page; a portion of the Results section; the Figure 1.; and, the mention of funding by NIH grant AI 23946:





Yours Truly decided to investigate more regarding the NIH grant award AI 23946 to Dr. Baric. Two more (of the multiple papers) funded by this grant are: one, for example, from 2005: “Coronavirus Genome Structure and Replication” [6]. Please see the screenshots, below, from this paper: the Title and Authors page; the Future Directions section; and, the Acknowledgements:




And, NIH grant AI 23946 also funded this paper by Dr. Baric, from 2009 [7], “Severe Acute Respiratory Syndrome Coronavirus nsp9 Dimerization Is Essential for Efficient Viral Growth.” Please see the screenshots from this paper, below: the Title page; the Summary; the Acknowledgements; and, the specific paragraph regarding the mouse hepatitis virus protein A59 (MHV-A59), which Dr. Baric was experimenting with back in 1986 (the Published Manuscript Number 11 [2], screenshots from which are above in today’s offering):



Below is the specific paragraph regarding MHV-59 and the nsp9 connection:

Dimerization is the process whereby two molecules of the same, or similar, chemical composition, join together to create a “dimer.”
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Yours Truly is aware that all the above may appear as a “long tale to tell.” However, the point is to “trace” how Dr. Baric used one particular NIH grant, AI 23946 (among many other NIH grants, to be sure) to help fund his research journey. Part One and Part Two discuss his experimenting with a mosquito-borne virus — to experiments with mouse hepatitis and mouse coronavirus proteins — to experiments with rabbit coronavirus proteins — to experiments of the recombination of mouse hepatitis and mouse coronavirus proteins — to experiments with inducing myocarditis and Congestive Heart Failure in rabbits injected with rabbit coronaviruses: experiments that, with the exception of the ones on the Sindbis virus, were funded, at least in part, by AI 23946.
Along the way of what may be called “the NIH grant AI 23946 aspect” of Dr. Baric’s research journey, one observes that the focus of work becomes more concentrated; the research and laboratory methods become more complex and sophisticated; and, the work on combining coronaviruses and how to create “new versions” of them is emphasized (in other words, Gain-of-Function research.)
It appears, in Yours Truly’s opinion, that what began as Dr. Baric’s research into a certain virus (the Sindbis virus) carried by a certain mosquito (his published manuscripts 1980 – 1984 [1]), had, certainly by the year 2009, evolved into something very different: a detailed study of, and development of, lab-application processes for coronavirus gene code combination, genome manipulation, and inducement of disease conditions — including heart issues and severe respiratory infection — from these combinations and manipulations.
Part Three will discuss NIH grant AI 23946 further, in addition to presenting other aspects of Dr. Baric’s research journey.
ALL COVID-19 “VACCINES” MUST BE REMOVED FROM THE MARKET AND FROM USE IN THE UNITED STATES. NOW.
ALL GAIN-OF-FUNCTION RESEARCH IN THE UNITED STATES MUST STOP. NOW.
THERE. MUST. BE. ACCOUNTABILITY.
THERE. MUST. BE. JUSTICE.
THERE. MUST. BE. TRUTH.
Peace, Good Energy, Respect: PAVACA
References:
[1]: “Curriculum Vitae Ralph S. Baric.” https://sph.unc.edu/wp-content/uploads/sites/112/2016/09/CV_Ralph_Baric.pdf.
[2]: “Recombination between non-segmented RNA genomes of murine coronaviruses.” Lai, M.M.C., Baric, R.S., Makino, S., Keck, J.G., Egbert, G.E., Leibowitz, J., Stohlman, S.A. https://pmc.ncbi.nlm.nih.gov/articles/PMC252599/pdf/jvirol00116-0117.pdf. 1986.
[3]: “Specific interaction between the coronavirus leader RNA sequences and the nucleocapsid protein.” Stohlman, S.A., Baric, R.S., Nelson, G., Soe, L., Deans, B. https://pmc.ncbi.nlm.nih.gov/articles/instance/253863/pdf/jvirol00090-0384.pdf. November 1988.
[4]: “Rabbit cardiomyopathy.” Baric, R.S., Edwards, S., Small, J.D. https://link.springer.com/chapter/10.1007/978-1-4684-5823-7_71#chapter-info. 1990.
[5]: “An experimental model for dilated cardiomyopathy after rabbit coronavirus infection.” L K Alexander, J D Small, S Edwards, R S Baric. https://doi.org/10.1093/infdis/166.5.978. November 1992.
[6]: “Coronavirus Genome Structure and Replication.” D.A. Brian, R.S. Baric. https://doi.org/10.1007/3-540-26765-4_1. 25 October 2005.
[7]: “Severe Acute Respiratory Syndrome Coronavirus nsp9 Dimerization Is Essential for Efficient Viral Growth.” Zachary J. Miknis, Eric F. Donaldson, Timothy C. Umland, Ryan A. Rimmer, Ralph S. Baric, L. Wayne Schultz. https://doi.org/10.1128/jvi.01505-08. 1 April 2009.
(Intellectual Property Disclaimer and Notice: With the exception of the linked published scientific papers and other linked items in the public domain listed above, the ideas, conclusions, and opinons in today’s offering are by PAVACA. Proper credit must be given to PAVACA if the ideas and conclusions of today’s offering are used by other blog writers, by podcasters, in social media, or in print media.)


































































































































