The colorized vintage image of vaccination for today’s header is courtesy of MedPage Today and Google Images.
Health Friday is a series devoted to Big Pharma, vaccines, general health, and associated topics. There are Important Notifications from our host, Wolf Moon; the Rules of our late, good Wheatie; and, certaincaveats from Yours Truly, of which readers should be aware. They are linked here. Note: AI-generated items in today’s offering will be cited as such. If readers wish to post AI-generated items in today’s discussion thread, they must cite their source. Thank you.
The Moderna “combination modRNA influenza + COVID-19 vaccine”, mRNA-1083, also called mCOMBRIAX, has just been approved for use in Europe. mRNA (mCOMBRIAX) is a combination of the Moderna modRNA multi-strain influenza “vaccine”, mRNA-1010, plus the company’s “other” modRNA COVID-19 bioweapon “vaccine”, mRNA-1283 (mNEXSPIKE.) Yours Truly has written about the mRNA-1010 component of this “combo vaccine” here: https://www.theqtree.com/2026/02/27/health-friday-2-27-2026-open-thread-modernas-mrna-1010-and-the-end-run-around-hhs-sec-kennedy-jr-part-one/; and, https://www.theqtree.com/2026/03/06/health-friday-3-6-2026-open-thread-modernas-mrna-1010-and-the-end-run-around-hhs-sec-kennedy-jr-part-two/. Part One of the discussion of the mRNA-1283 (mNEXSPIKE) component is here: https://www.theqtree.com/2026/03/13/health-friday-3-13-2026-open-thread-meet-modernas-mrna-1283-mnexspike-the-other-component-of-mrna-1083-mcombriax-part-one/.
Today’s offering is Part Two of two regarding mRNA-1283 (mNEXSPIKE.)
The Package Insert for healthcare professionals for mNEXSPIKE is here: https://www.fda.gov/media/186738/download. Below is a screenshot of section 11 Description of this injectable:
Note that the Description does NOT mention that the fact that N1-Methylpseudouridine (either by that name, or by its IUPAC name [its spelled-out chemical components name]) is used in mNEXSPIKE. Nor does it mention that the N1-Methylpseudouridine in mNEXSPIKE serves as the “scaffold” for the mechanism of the “vaccine” — a lab-created element that destroys the RNA of the natural Uridine in the body, replacing it with a compound that does nothing beneficial: in fact, which serves as a “facilitator” in speeding the ingredients of the “vaccine” throughout the entire body; while, at the same time, severely damaging the body’s natural ability (via natural Uridine and its RNA) to regulate mood, help with learning and memory, and assist in normal “gut-brain axis” interactions.
Which leads into the Patent for mNEXSPIKE. Yours Truly will not present the entire Patent. Nor is Yours Truly advising people to read through the Patent document for every drug or “vaccine” they put into their body. However, there are multiple aspects of “the Devil is in the details” in the Patent for mNEXSPIKE regarding the ingredients that “may” be used in formulating this “vaccine” — details that appear to be lacking in the Package Insert. Keep this in mind when reading the following.
There are multiple Moderna-held Patents for mNEXSPIKE (https://www.modernatx.com/en-US/patents.) The most recent Patent is here: https://patents.google.com/patent/US12508278B2/en. The Title of the Patent is: “Lipid nanoparticle compositions and methods of formulating the same.” This Patent was published on 30 December 2025. An image of the Inventors and Dates section is below:
Note that the assigned Agent for this Patent is ARES CAPITAL CORPORATION (https://www.arescapitalcorp.com/), which is private-equity, real estate, and credit asset manager in “global alternative investment” (per Wikipedia.)
The mention of N1-Methylpseudouridine as a component of mNEXSPIKE is here in the Patent:
Which is followed by a list, in Claim 1, of twenty-two different “phospholipids” that Moderna “may” choose from in formulating the “vaccine.” Which list is then followed by a list, also in Claim 1, of nine different PEG-lipids (polyethylene glycol lipids) that Moderna “may” choose from in formulating the “vaccine.” The question here is: Are there different “phospholipids” and/or different “PEG-lipids” being used in different batches of mNEXSPIKE other than the ones listed in the section 11 Description of the Package Insert for the “vaccine”? Recall, from Part One regarding mNEXSPIKE, that the FDA Approval Letter that was sent to Moderna for this injectable specifically stated that the agency relied ONLY on the “data” and other information that Moderna gave to the FDA — there was no independent testing or analysis performed.
Then, there is the lipid nanoparticle (LNP) in mNEXSPIKE, which in the section 11 Description is SM-102. However, in the Patent document, there appear to be multiple types of LNPs from which Moderna “may” choose in formulating the “vaccine.” In addition, there are listed multiple percentage ratio ranges of these LNPs in multiple types of combinations with the PEG-lipids and/or with “non-cationic lipids.” These are in the Patent document under 1. Lipid Nanoparticle Compositions. The question here is: Are there then multiple “variations” of these formulations that would appear in different batches of mNEXSPIKE?
Then, there are the “Adduct Impurities” that are permitted in the formulation of mNEXSPIKE. Please see the screenshot, below, from the Patent, the section 1. Lipid Nanoparticles:
“Adduct impurities” — think the “loose DNA” in the Pfizer-BioNTech and in the Moderna modRNA COVID-19 bioweapon “vaccines.” Think the “Process 2” manufacturing method — and that “culturing bath” of lab-created E. coli derivative that is part of this process — that these companies use as part of modRNA COVID-19 bioweapon “vaccines” production. It appears that Moderna is fine with allowing impurities in mNEXSPIKE. One would think that, after more than five years of manufacturing modRNA COVID-19 bioweapon “vaccines”, the company would have come up with a way to remove impurities; or, at least, to reduce the percentage “allowed” in the “vaccine” to as nearly zero as possible, from the product before putting it on the market — and not allowing a range of percentage amounts of impurities to remain in the product.
Following are screenshots from the Patent US12508278B2 for mNEXSPIKE. Yours Truly believes it appears that Moderna may have submitted “data” to the FDA for approval of this “vaccine” based on only the limited set of ingredients that the company sent “data” about — while, at the same time, the Patent for the “vaccine” contains multiple lists of multiple variations of these ingredients from which the company “may” choose to formulate batches of the “vaccine.” In other words — is a “How Bad is My Batch?”-type of scenario being set up?
The ratio of lipid nanoparticles (LNPs) to the mRNA in mNEXSPIKE is allowed to vary:
The type of pseudouridine used in mNEXSPIKE is allowed to vary:
Which indicates that another pseudouridine OTHER than N1-Methylpseudouridine “may” be used in mNEXSPIKE.
The company reserves the right to substitute codons in the manufacture of mNEXSPIKE. Codons are three-nucleotide sequences of a strand of either DNA or of RNA:
The “rationale” for codon replacements:
Forms of administration for mNEXSPIKE:
Note that the Patent states that the “vaccine” can cross the Blood-Brain Barrier.
In summary: It appears that Moderna, in giving the FDA “data” involving the ingredients listed on the Package Insert for mNEXSPIKE, for which “data” the FDA granted “full approval” last year, did not inform the FDA that the Patent for the “vaccine” contains multiple variations for the ingredients used in the product; multiple variations of formulations for the product; and multiple forms of administration of the product. It also appears that Dr. David Kaslow, who signed the FDA Approval Letter to Moderna for mNEXSPIKE, either did not read the Patent document for this product; or, did not have it summarized for him to read; or, read either or both of the latter and was fine with it.
**** AND HERE’S THE REASON BEHIND THE DISCUSSION OF THE PATENT FOR mRNA-1283 (mNEXSPIKE) AND THE SCREENSHOTS FROM THE PATENT: It appears that Moderna is using clinical trials study subjects as HUMAN LAB RATS in their two latest Clinical Trials of “variant formulations” of mRNA-1283 (mNEXSPIKE.)
Clinical Trial NCT07266558 (https://clinicaltrials.gov/study/NCT07266558.) Please see below: screenshots of the study Overview, and of the Trial Description – Intervention and Study Arms section from the Researcher View:
Note the language, “Variant Formulation.” Note ALSO that this Clinical Trial is for HEALTHY persons age 50 – 64 years with NO underlying conditions — this appears to be the “setup” to getting mNEXSPIKE approved by the FDA for HEALTHY persons under age 65. Note also that mRNA-1273 (SPIKEVAX) may be given to a study subject.
Clinical Trial NCT07089706 (https://clinicaltrials.gov/study/NCT07089706.) Please see below: screenshots of the study Overview, and of the Trial Description – Intervention and Study Arms from the Researcher View:
Note that there is NO saline Placebo group in the clinical trial above. Note also the very small study subject pool (832 persons.)
What are in these “variant formulations” of mRNA-1283 (mNEXSPIKE) that the study subjects will receive in the clinical trials listed above? Refer back to the screenshots from the Patent for mRNA-1283 in today’s offering. Look at the multiple combinations of lipid nanoparticles to modRNA, the multiple types of pseudouridines, the multiple percentage ranges of allowed “adduct impurities” that can be used in formulations of this injectable. Also — Why is there NO saline Placebo group in NCT07089706?
Does anyone at the FDA understand what’s going on here?
THERE IS NO PLACE FOR AN mRNA, A modRNA, AN saRNA, OR A taRNA PRODUCT IN THE HUMAN BODY, IN ANY FORM. THERE MUST, FIRST, BE MUCH MORE RESEARCH PERFORMED ON THESE GENE-ALTERING THERAPY PLATFORMS AND PRODUCTS. THERE MUST, SECOND, BE IRREFUTABLE PROOF THAT PRODUCTS MADE USING THESE THERAPY PLATFORMS AND PRODUCTS ARE TRULY “SAFE AND EFFECTIVE.”
Peace, Good Energy, Respect: PAVACA
(Intellectual Disclaimer and Notice: Other than URLs and related items available on the Internet, the ideas and opinions of today’s offering are by PAVACA. Credit must be given to PAVACA if the ideas and opinions of today’s offering are used by other blog writers, by podcasters, or in social or print media.)
Deeply held faith meets secular “security” concerns.
Open Letter to the White House Faith Office
AN OPEN LETTER TO THE WHITE HOUSE FAITH OFFICE
From Terpsehore Maras — Orthodox Christian
Dear Pastor Paula White-Cain, Jennifer Korn, and the entire White House Faith Office,
I am writing to you not as a distant observer of this crisis, but as an Orthodox Christian who has stood inside the Church of the Holy Sepulchre in Jerusalem — who has felt the incense, the candlelight, the weight of seventeen centuries of unbroken prayer press against my chest and change me in ways I am still unable to fully articulate. That church is sealed. It has been sealed since February 28. And as I write this, Holy Week is twelve days away.
I am also writing to you as an American. As someone who believes, genuinely and without irony, that this country’s commitment to religious freedom is one of the finest things about it — and that commitment means nothing if it is applied only when convenient, only to allies we feel comfortable pressuring, only to denominations that vote in predictable blocs. You were appointed to your positions because this President declared that faith matters in the halls of power. I took that seriously. I am asking you to take it seriously now.
The Church of the Holy Sepulchre is not simply a historic landmark. It is the beating heart of Christianity itself — the site of the Crucifixion, the Burial, and the Resurrection of Jesus Christ. It is where, every Holy Saturday since at least the fourth century, the Patriarch of Jerusalem has entered the tomb and emerged carrying the Holy Fire — a flame that Orthodox and Oriental Christians across the entire world receive as a direct sign of the living God. Since 1988 that flame has traveled from Jerusalem to Athens, to Sofia, to Belgrade, to Bucharest, to Moscow, to the diaspora churches of America without interruption — through wars, through crises, through a global pandemic. This year, for the first time, it may not travel at all. Not because the building is rubble. Not because the Patriarch is unable. But because the keys are in the hands of a government that has spent years making Christian worship in Jerusalem increasingly difficult, and that has now, under the cover of a genuine security emergency, locked the door entirely.
I need you to understand who is being shut out. This is not one community. This is the fullness of ancient Christianity — Greek Orthodox, Russian Orthodox, Serbian, Romanian, Bulgarian, and Antiochian faithful who have prayed at that site for as long as their nations have existed. It is the Ethiopian Orthodox Tewahedo Church, one of the oldest Christian bodies on earth, whose monks have kept a continuous presence on the roof of the Holy Sepulchre itself for centuries. It is the Coptic Orthodox Church of Alexandria, founded by the Apostle Mark, whose people have suffered enough in this generation without losing Easter too. It is the Assyrian Christians — the oldest continuously Christian community in the world, who speak the language of Christ, who survived genocide, who were driven from their ancient homeland in Mesopotamia, and who have never, through any of it, stopped celebrating the Resurrection. It is the Armenian Apostolic Church — the first Christian nation on earth — a people who know better than almost anyone what it means to have their faith and their existence threatened simultaneously. And it is the millions of American faithful from every one of these traditions — your neighbors, your fellow citizens, people who love this country and who are watching your office right now with a very specific question in their hearts: does our Easter matter to you?
I am Orthodox. I want to be honest with you about something: we are not afraid. Our faith does not permit it. The Psalmist asked, “The Lord is my light and my salvation — whom shall I fear?” St. Paul wrote from prison that neither death, nor life, nor principalities, nor powers, nor things present, nor things to come shall separate us from the love of God. St. Barsanuphius the Great told us to have God and fear nothing. Elder Ephraim of the Holy Mountain told us that before the power of Christ, all threats are destroyed. We believe these things with our whole lives — we proved it during COVID when we shared one spoon for Communion because God is almighty and nothing happens without His say. We are prepared to walk through that door and accept whatever risk is on the other side. We are not asking to be protected. Our God will do that as He sees fit. We are asking to be permitted.
That permission is within your reach. The U.S. Ambassador to Israel can make a formal request today — this week — that a clergy-only Holy Fire ceremony be permitted on Holy Saturday, April 11, under whatever security conditions Israeli authorities require. It was done during COVID. The precedent exists. A public statement from the President or from your office expressing concern about Christian access to Easter services in Jerusalem would cost nothing diplomatically and mean everything spiritually to hundreds of millions of people. Active U.S. support for the negotiations already underway between the patriarchates and Israeli authorities could tip the balance before Holy Week begins on March 29.
This is your moment. Not a hypothetical future moment — this one, right now, with less than two weeks on the clock. The White House Faith Office was created to be a direct line between the faith community and the executive branch. Here we are. Here I am. I am asking you, directly, to use that line.
The tomb of Christ should not be locked at Easter because no one in the White House picked up the phone. Every ancient Christian community on earth — communities that have survived Roman persecution, Byzantine politics, Ottoman rule, Soviet suppression, genocide, and exile — is watching to see whether the most powerful government on earth will spend thirty minutes of diplomatic capital on their behalf.
History will record what this office did in these days. And what it did not do.
In faith and in urgency,
Terpsehore Maras
Orthodox Christian | Washington, March 2026
+++
My prayer:
Holy God, may the Holy Fire of your Son’s resurrection be seen by all the world!
https://grokipedia.com/page/Holy_Fire#orthodox-theological-description
Amen!
I’m still working my way through the Grokipedia article.
Just wow.
https://grokipedia.com/page/Holy_Fire#ottoman-era
This post was scheduled at 12:01 AM and missed publication immediately at that time. I watched every minute after that – it was kicked out and published at 12:06 AM.
I was watching too. I saw on the dashboard the message that it had missed it’s scheduled time, and then the new kicker outer finally got in there.
We’ll see how long this lasts. Hope for the best!
Indeed.
Less than eight minutes…..
Actually 4 or 5 minutes.
And T3 slapped a comment on it within a minute or two. Tricky.
LOL.
No tricks involved.
Just was watching with curiosity!
Dear PAVACA, Thank you for all your work.
It stuns me that our FDA is still approving vaccine studies that lack a saline placebo.
For Aubergine.
Christ Pantocrator
Christ is Almighty/King/Ruler of All
https://russianicon.com/the-meaning-of-christ-pantocrator-in-christian-art
My favorite from Hagia Sophia.
Hagia Sophia was built as the cathedral of Constantinople between 532 and 537 CE.
US Mint gets green light to put Trump on 250th gold coin
Pres. Trump deserves this.
https://twitter.com/dom_lucre/status/2034815209294995702
The news blurb doesn’t report that some women are saying that he groomed and sexually assaulted girls. There are lots of streets, schools, buildings and the like named after him.