NIH and Gilead Blamecasting Remdesivir Renal Toxicity to an Excipient

Well, they can lock us out of The Q Tree, but they can’t stop the truth from getting out.

Enjoy a post first over on The U Tree and now HERE.

Here is a quickie in my WAR ON REMDESIVIR.

Fellow Treeper barkerjim dropped an interesting document today, from back in July, which showed the NIH mentioning black sheep IVERMECTIN on the same page as REMDESIVIR.



Such a beautiful misdirection. These guys are MAGICIANS.

This is a perfect example of my postulate that fighting FOR ivermectin will not yield results for restoring real science as fast as fighting AGAINST remdesivir.

In fact, I would go so far as to say that the enemy realized that getting us to fight FOR the saving drug would keep us from expending our energy fighting AGAINST the murdering drug that kills us off and gives them money for doing it.

You may recall my previous posts about remdesivir.

Remdesivir Is How We Bring Down The Temple of Faucism

The Murder of Veronica Wolski by Fauci and Gilead’s Zyklon D

My next piece was going to be an expansion on Karl Denninger’s recent post which places remdesivir/ivermectin and remdesivir/hydroxychloroquine in the context of Anthony Fauci and the disturbingly similar case when he was “all about AIDS” – namely, AZT/bactrim.


YES. As Cthulhu has said before, “This is not Fauci’s first rodeo.”

Before there were hydroxychloroquine and ivermectin as innocent victims – good Samaritans accused falsely before the world – there was BACTRIM.

And there was FAUCI on all of them. AZT played the murderous part of remdesivir long before we forgot that “miracle drug”.

However, this new information from barkerjim’s drop right here needs to get out right away. The Q Tree site was brought down YET AGAIN as I started working on this, and again when I resumed, so I know it’s critical stuff. The ChiComs have a huge investment – both financial and military 4GW – in the American-killing drug remdesivir. They WILL protect it.

We know from doctors and scientists quoted in my first two articles, that remdesivir has a horrible track record – shocking, really – of renal toxicity. Studies of the drug against Ebola were TERMINATED because it was killing people in the hospital.

How déjà vu.

But here it comes again.

I read the same study results that the above celebratory announcement was made over. Those results were nothing to cheer about, with shot kidneys just the horrifying icing on the death cake. In my opinion, the results were far WORSE than any prior results for hydroxychloroquine. The results – to me – made HCQ look EXCELLENT in comparison.

Yes – by controlling what is acceptable science and what is not, Fauci was able to force the world to field a BAD, DANGEROUS DRUG that made money for Gilead, over a safe, mildly (but critically) effective drug, that made money only for the generics industry, and a French company.

And to top it off, Fauci USED Trump, who could do absolutely nothing about it, to take a KILLER drug into market as the ONLY way to treat his little pandemic.

So let’s take a look at that page dropped by barkerjim. I have captured it as SIX IMAGES.

Again, the link:

As you can see by our comments on The U Tree, most people will look at this table and think they are seeing positive and reasonable behavior by NIH. Adverse events are being discussed, and it appears that things are “even-handed” between different drugs.

And that is EXACTLY the style in which EVIL ABOUNDS IN WASHINGTON, DC (or Atlanta). Good and evil are forced into compromises where GOOD LOSES and EVIL WINS – but the result is called “meeting in the middle”.

CLOSER INSPECTION of the table gives you this, under Adverse Events for remdesivir.

  • Nausea
  • ALT and AST elevations
  • Hypersensitivity
  • Increases in prothrombin time
  • Drug vehicle is SBECD, which has been associated with renal and liver toxicity. SBECD accumulation may occur in patients with moderate or severe renal impairment.
  • Each 100 mg vial of RDV lyophilized powder contains 3 g of SBECD, and each 100 mg/20 mL vial of RDV solution contains 6 g of SBECD.
  • Clinicians may consider preferentially using the lyophilized powder formulation (which contains less SBECD) in patients with renal impairment.

This is some of the most remarkable “medical misinformation” I’ve ever seen. It’s truly a work of art.

NIH has HIDDEN – completely hidden – the pronounced renal toxicity of remdesivir. They have hidden it COMPLETELY. It’s GONE. What you are seeing there – the talk about renal and liver toxicity – is a BLAME-SHIFT to a substance that is used WIDELY in intravenous formulations, called sulfobutylether-β-cyclodextrin, or SBECD for short.

This substance is an EXCIPIENT.

An excipient is a substance that is used to MIX with a drug, and take that drug into a form where it can be ADMINISTERED easily. Thus, an excipient may DISSOLVE the drug, or help to dissolve it, into a liquid form. It may help POWDER the drug, so that it can be pressed into tablets or filled into capsules.

Excipients are often considered “inactive ingredients”, even though – YES – they very much can change the effective amount of a drug that the patient gets.

If I had to describe SBECD as something, it would be as a DETERGENT FOR DRUGS. It’s a kind of SOAP made from a cyclodextrin, instead of from some kind of fat or lipid.

And what is a cyclodextrin?

Cyclodextrins are rings of sugar molecules that falls somewhere in between being a smaller chain sugar (like sucrose) and a starch. Cyclodextrins have lots of uses, because they form tubes that act like waffle cones for other molecules. Febreze uses cyclodextrins to trap molecules which have unpleasant odors, at the same time that they release more pleasant ones. A genius application, quite frankly.

Thus, if you make a SOAP that has a little waffle cone for drugs, you can EASILY get drugs to dissolve into a concentrated liquid form by using that soap.

See those sidechains hanging off the cyclodextrin ring? Those are the “SBE” part of SBECD. They are typical of DETERGENTS.

This SBECD stuff and things like it are VERY useful for delivery of drugs. AND they’re relatively safe, too. They are rapidly excreted through the kidneys. Yeah, you don’t want a SOAP piling up in your blood if your kidneys are not working, and THAT is the fact that is being TWISTED by NIH when they say:

Drug vehicle is SBECD, which has been associated with renal and liver toxicity. SBECD accumulation may occur in patients with moderate or severe renal impairment.

Did you catch that sleight of hand? I’m gonna show it to you.

What exactly is causing the renal problems in the FIRST PLACE that you MAY have to be careful about, so that you don’t build up the excipient FOR IT, which MAY constitute a FURTHER risk?


It’s a crafty little lie. If you have good kidneys, you don’t have anything to worry about with this SBECD crap. But if you have bad kidneys, the LEAST of your problems is SBECD buildup. It’s the remdesivir IN the SBECD that’s gonna kill you.

Weakened kidneys do NOT need to be hit with remdesivir.

Which doesn’t even work ANYWAY. Except to keep people LONGER in the hospital.

Now what you SHOULD be getting, when they administer remdesivir, at the point where the VIRUS is basically gone, and you’re dealing with spike protein damage, cytokine storm, and all that nasty crap, are antiinflammatory, antithrombotic, and immunomodulatory drugs. Even HCQ (a known antirheumatic) at reasonable doses had some antiinflammatory effect in late-stage hospitalized COVID cases, although steroids and other things work better.

When the virus is basically gone, and a bunch of its CRAP is left behind, there is no point administering a toxic antiviral like remdesivir, other than to send money to Gilead Pharmaceuticals and their Deep State friends.

Now, let me stop here and validate this stuff.

HERE is a link that explains how SBECD can be filtered out of blood ANYWAY if a patient has renal impairment.


Do you see what that means? SBECD is a nothingburger. It’s a DEFLECTION.

The renal problems of remdesivir are never mentioned, by quickly bringing up the risks of the excipient due to the unmentioned damage BY remdesivir.

What NIH did here was to quickly point their finger at THE OTHER GUY and said “HE DID IT!”

This is pure politicized science, where the politics is to defend the drugs and vaccines that enable the shared profits of both the Deep State and the companies that NIH, CDC, and NIAID are in bed with.

Let’s go back to that link I just gave you. THIS part of the conclusions comports very nicely with the reality of SBECD as a widely used excipient.

The finding that SBECD can be effectively removed by CVVH is clinically important, because some cyclodextrins have been associated with hepatotoxicity or nephrotoxicity due to vacuolation [3]. Although our study was small, no evidence to suggest SBECD as a cause of hepatotoxicity or nephrotoxicity was demonstrated in our study patients. This finding is consistent with other SBECD safety studies in humans [3,18]. Additionally, animal studies have only been able to demonstrate cyclodextrin toxicities when dosages more than 50-fold greater (3,000 mg/kg) than those used in humans were administered [3,19,20]. Unlike other cyclodextrins used in these animal studies, SBECD undergoes only minimal tubular reabsorption and limits concentrations within the intracellular tissues of the kidney, potentially reducing the risk of nephrotoxicity. Nevertheless, the FDA labeling for voriconazole recommends that IV therapy be avoided, if possible, in patients with a CrCl <50 ml/min [5]. Our data suggest that IV voriconazole can be safely administered in this population if the patient is concurrently undergoing CVVH.

But if you don’t believe THAT study, try THIS ONE.


Clinical Trial J Clin Pharmacol

2018 Jun; 58(6):814-822. doi: 10.1002/jcph.1077.  Epub 2018 Mar 26.

Clinical Pharmacokinetics of Sulfobutylether-β-Cyclodextrin in Patients With Varying Degrees of Renal Impairment

Randall K Hoover 1Harry Alcorn Jr 2Laura Lawrence 3Susan K Paulson 4Megan Quintas 3David R Luke 3Sue K Cammarata 3Affiliations expand

Free PMC article


Delafloxacin, a fluoroquinolone, has activity against Gram-positive organisms including methicillin-resistant S aureus and fluoroquinolone-susceptible and -resistant Gram-negative organisms. The intravenous formulation of delafloxacin contains the excipient sulfobutylether-β-cyclodextrin (SBECD), which is eliminated by renal filtration. This study examined the pharmacokinetics and safety of SBECD after single intravenous (IV) infusions in subjects with renal impairment. The study was an open-label, parallel-group, crossover study in subjects with normal renal function or mild, moderate, or severe renal impairment, and those with end-stage renal disease undergoing hemodialysis. Subjects received 300 mg delafloxacin IV or placebo IV, containing 2400 mg SBECD, in 2 periods separated by ≥14-day washouts. SBECD total clearance decreased with decreasing renal function, with a corresponding increase in area under the concentration-time curve (AUC0-∞ ). After IV delafloxacin 300 mg administration, SBECD mean total clearance was 6.28 and 1.24 L/h, mean AUC0-∞ was 387 and 2130 h·μg/mL, and mean renal clearance was 5.36 and 1.14 L/h in normal and severe renal subjects, respectively. Similar values were obtained after IV placebo administration. In subjects with end-stage renal disease, delafloxacin 300 mg IV produced mean SBECD AUC0-48 values of 2715 and 7861 h·μg/mL when dosed before and after hemodialysis, respectively. Total SBECD clearance exhibited linear relationships to estimated glomerular filtration rate and creatinine clearance. Single doses of IV delafloxacin 300 mg and IV placebo were well tolerated in all groups. In conclusion, decreasing renal function causes reduced SBECD clearance and increased exposures, but SBECD continues to exhibit a good safety and tolerability profile in IV formulations.

Keywords: Delafloxacin; Hemodialysis; Pharmacokinetics; Renal Dysfunction; Sulfobutylether-β-cyclodextrin.

I’m going to repeat that.

In conclusion, decreasing renal function causes reduced SBECD clearance and increased exposures, but SBECD continues to exhibit a good safety and tolerability profile in IV formulations.

Now, the above is not the only “New York Times” style trick that NIH plays here.

Let me list, without going into long-winded explanations, my additional favorites.

  • The table authors note that clinical drug-drug interaction studies have not been done, but nonetheless, they say “CQ or HCQ may decrease the antiviral activity of RDV; coadministration of these drugs is not recommended.1” – with a hanging reference.
  • For three OTHER potential drug interactions, communications from Gilead are cited as sufficiently exonerating. One is a non-competing generic steroid (dexamethasone) and the other two are patented big pharma antivirals from corporate “frenemy” Genentech. The interaction and “C-level mind-melding” between these two companies is very interesting. Look who just went from one to the other. Interesting times.
  • Some crafty shade is thrown at ivermectin by citing a possible adverse event risk and then retracting it, lawyer-style: “Neurological AEs have been reported when IVM has been used to treat parasitic diseases, but it is not clear whether these AEs were caused by IVM or the underlying conditions.” Meanwhile, the DEMONSTRATED risks of remdesivir are not even mentioned.

Bottom line – NIH is protecting Gilead on the toxicity of remdesivir, and they used FAKE NEWS tricks to do it. I keep telling people – science journalism is bad, and science governance is WORSE. It’s been CHINATIZED and OBAMATIZED.

And we’re going to UNDO THAT.


5 4 votes
Article Rating
Notify of
Newest Most Voted
Inline Feedbacks
View all comments


So, I am going to post something seemingly unrelated. It is a different area completely, but the similarities are stark and jump out at you. Both are about the “science” of complex systems and the PROTECTION RACKETS that have sprung up to profit from the CREATED FAKE FEAR. In both cases, the “solutions” are non solutions, or better yet, make the problem WORSE, ensuring that the RACKET NEVER ENDS as a result of their solutions. They hide behind the complexity in order to PERPETUALLY obfuscate.

What follows is a comment I made to MSM article earlier today, and it is resonating like crazy. People can see the truth in it.


What we do know is that large scale photovoltaic plants create their own “heat island” effect.

Another thing we know is that wind turbines ALSO result in net heating. They reduce average surface wind speeds (duh) which reduce their evaporative cooling effect. More importantly, winds are generated by thermal convective uplift (heat transport from the surface to altitude, then out to space) which create a surface low pressure region. This low pressure is filled with inrushing surface air AKA “wind”. Reducing the speed of this wind actually retards thermal uplift. It is this fact (which has been studied, modelled and published) which is NEVER mentioned by the doom mongers.

What I am pointing to is that it is known that the primary solutions to Global Warming make the “problem” worse – and nobody talks about it. What on earth is that about?

If you offer solutions to a problem that is never solved, but your ineffective “solutions” are never publicly questioned, what exactly do have? A permanent demand for your “products” is one answer that springs to mind ………….

Last edited 2 years ago by JasonD
Gail Combs

Early on there was a study (shouted down of course) that showed it TAKES more energy to MAKE bio-fuel than is produced.

Study: Ethanol Production Consumes Six Units Of Energy To Produce Just One (Science Daily)

Ethanol Fuel From Corn Faulted As “Unsustainable Subsidized Food Burning” In Analysis By Cornell Scientist (Science Daily)

But hey, ADM made a KILLING and so did Monsanto.
(I am not going to try and find those references)

Archer Daniels Midland, the largest U.S. ethanol producer, is planning to open a biodiesel plant in Indonesia with Wilmar International Ltd. this year and a wholly owned biodiesel plant in Brazil before July, the Wall Street Journal reported on Thursday. The Brazil plant is expected to be the nation’s largest, the paper said. Worldwide, the company projects a fourfold rise in biodiesel production over the next five years. ADM was not immediately available to comment. Reuters – Feb. 16, 2007.,9171,1725975,00.html

The Clean Energy Scam – The U.S. quintupled its production of ethanol–ethyl alcohol, a fuel distilled from plant matter–in the past decade, and Washington has just mandated another fivefold increase in renewable fuels over the next decade. Europe has similarly aggressive biofuel mandates and subsidies, and Brazil’s filling stations no longer even offer plain gasoline. Worldwide investment in biofuels rose from $5 billion in 1995 to $38 billion in 2005 and is expected to top $100 billion by 2010, thanks to investors like Richard Branson and George Soros, GE and BP, Ford and Shell, Cargill and the Carlyle Group.

The UN even saw the problem.

Biofuels ‘crime against humanity’ – Massive production of biofuels is “a crime against humanity” because of its impact on global food prices, a UN official has told German radio. “Producing biofuels today is a crime against humanity,” UN Special Rapporteur for the Right to Food Jean Ziegler told Bayerischer Runfunk radio. Many observers have warned that using arable land to produce crops for biofuels has reduced surfaces available to grow food. Mr Ziegler called on the International Monetary Fund (IMF) to change its policies on agricultural subsidies and to stop supporting only programs aimed at debt reduction. He says agriculture should also be subsidised in regions where it ensures the survival of local populations. Meanwhile, in response to a call by the IMF and World Bank over the weekend to a food crisis that is stoking violence and political instability, German Foreign Minister Peer Steinbrueck gave his tacit backing.

Corn is a BIG FEEDER using up a lot of nutrients. It also can cause a lot of soil erosion.

And then there is WATER USE:
Here are some references.
One third to one half of water pumped over from the western slope is used for agriculture.

Over 90 percent of water consumed through human activities in Colorado occurs in agriculture.

Mesa County is the largest water user in the state. It is almost all agricultural and is 99% surface water. Weld County is the largest corn producer and the second largest water user in the state. 80% of the water used in Weld County is surface water.

One third of corn production in the US is for biofuels.

Good luck trying to grow corn in Colorado or Arizona without irrigation. Most of the corn growing regions receive 15 inches of precipitation or less per annum.

Inclusive of the fact that they are at least as carcinogenic for the acetaldehydes and formaldehydes formed and (est.) to result in ~10% higher incidence of asthma, emphysema and other pulmonary diseases.
Perhaps not the point, herein, but at least as relevant~
h ttp://


Australia is about to invest “bigly” in “hydrogen energy”. Hydrogen produced by “green” energy tech. The only problem is, hydrogen reacts with ozone. It took me 1 second of web searching to confirm what my common sense screamed at me – both ozone and hydrogen are extremely reactive.

Multiple of their own “studies” done from the 70’s to the late “oughts” demonstrate this.
So their big poster child – the Montreal Protocol is going to be ignored as everybody climbs onto this new bandwagon.
Every “solution” they come up with makes the “problem” worse.


Yup. The wages of sin is death. When you are filled with sin, you sow death. As you are so ably showing us, they are profiting from making us sicker. My example above is that they are doing the same on an environmental scale. As you said, on any scale, in any way.
This is now being done on all 4 corners of the earth. The 4 horsemen have reached their destinations ……..

WATCH THE WATER – I will be explaining myself in much more detail – without revealing the full extent of what is coming, thanks to you wise caution back in April/May re not sharing plans.

Deplorable Patriot

Thank you for this as we go into the cold and flu season and one of the shot up people in my family has kidney issues.

I’m not sure they will listen to me, though.


Very difficult situation.

Pray. Trust. Wait.

God is working when it seems the situation is at an impasse.

Deplorable Patriot

Yes, well, my mom’s cousin passed away this morning. That’s two of her first cousins since Christmas. He was pretty sick with the ailments of an old man, but still.

Valerie Curren

Sorry for another loss in your extended family.  😞 

Deplorable Patriot

The one good thing…,my dad loves berries. So, for snacks I’ve been getting dried berries, and he’ll eat them by the bag, so at least there’s that.


This mentions zyrtec and other simple measures.
A local doctor is having patients with lingering GI issues take it daily.

Sue Palmer

FYI, in Molnupiravir trials/Phase II/III, “Molnupiravir has not been shown effective in treating or preventing COVID-19 and may have harmful side effects and consequences.” I can send anyone the full report if requested.


Great post!

Brave and Free

Great information Wolf. Thanks again for all your hard work. I am sure glad you’re on our side!


Amen to that ..


Tricksy. Very tricksy.

But we won’t let them get away with it.

Thank you so much for seeing things and explaining them to us. Your insight and knowledge is invaluable to us here. ❤🤍💙


Just checking over here, let’s see what happens .. 😐


.. huh … what do you know .. it worked .. 😬

Concerned Virginian

Wolf Moon
Thank you for another great article!
Guess who are among the top 10 shareholders of Gilead (Gilead Sciences Inc.)? —
BlackRock Fund Investors: 77,779,661 shares;
Vanguard Group: 99,724,620 shares;
BlackRock Investment Management, UK: 15,080,884 shares.

Deplorable Patriot



Valerie Curren

For some reason piracy comes to mind…predictive programming?
comment image
comment image
comment image
comment image

Gail Combs

I put up three more papers on Remdesivir on the U-Tree.
The University Of Cincinnati study
The study is published in the journal Fundamental & Clinical Pharmacology.

“….In the UC study, lead author Bingfang Yan, a pharmaceutical scientist, and his UC graduate students Yue Shen and William Eades, found that the drug permanently stops the activity of an enzyme called CES-2, which is found in the intestine, liver and kidney and is needed for the breakdown of many medications….”

Valerie Curren

Excellent catch & exposure–keep up the Great Work boss. God Bless YOU!!!

Valerie Curren

YW Hope you are archiving All of your great CV & gov’t tyranny work at & the other sites they recommend when they don’t have something saved there…

[…] NIH and Gilead Blamecasting Remdesivir Renal Toxicity to an Excipient […]

[…] BAD MOVE. […]