This DePat Tuesday Open Thread honors the author of the original Tuesday open thread on this site, namely the late Susie Sampson, a.k.a. Deplorable Patriot, among her other handles, pen names, etc.

For more on the untimely passing of Dear DePat, please see these three posts.
At one time, DePat handled FOUR daily open threads here, in addition to taking care of her relatives, choir duties, and numerous other responsibilities. She was a powerhouse – a dynamo – a true force of nature.
DePat’s faith in Trump, Q, “The Plan”, the White Hats, and “the anons” in general, was legendary. Although I didn’t always agree with her quick acceptance of some sketchier evidence and fringier theories, I will gladly admit to “coming around” to numerous so-called “conspiracy theories” which she championed first. I was always careful to give her credit for being right, too, when I had been wrong.
It is impossible to overstate how much DePat did for not only this site, but for her country. I urge all to say a quick prayer of thanks, whenever you think of her, for the privilege of knowing, in life or after death, such an exemplary human being, and lover of God.
And thank you, Susie, for the firm foundation which you left us, when you were called to your true home!


Is There Another Cell Nucleus Hall Pass in the New mRNA Flu Vaccine, mFlusiva?
Let’s start off with some history.
Are you aware of the fact that both the Moderna AND the Pfizer COVID vaccines contained a genetic sequence that acts like a “hall pass” or “VIP ticket”, allowing the holder to get into the nucleus of human cells?
Here is a post where I explained this.
Were it not for somebody dropping a link to an obscure paper in my Twitter timeline back in early 2023, I would have never realized how extra sketchy that made both the virus and the vaccines – and especially the latter, since it would have been theoretically possible to remove the nuclear hall pass from the spike protein used as the vaccine.
Let me repeat that. They left the “hall pass” in the mRNA code for the vaccine.
But – and I have to stress this – it was not just that this “hall pass” was there. No. It was much worse. The paper in question was experimental, and it showed that the viral spike protein not only contained the hall pass, but that it WORKED. The hall pass actually worked to get the spike protein into the nucleus. They even had PICTURES of it in the nucleus.
LINK: https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1073789/full
BUT WAIT! THERE’S MORE!
The hall pass not only got the spike protein into the nucleus – the spike protein THEN got the mRNA that coded for it into the nucleus, as well.
Yes. You are reading that correctly. The spike protein of SARS-CoV-2 has a known sequence in it that ends up getting both IT and the mRNA that created it, into the cell nucleus.
One would THINK that this might be a big deal. Especially after we were REASSURED that NO, VIRGINIA – THE mRNA WILL NEVER, EVER GET INTO THE CELL NUCLEUS, YOU FOOLISH VACCINE SKEPTICS.
Are you seeing why this is kind of a big deal?
SO – NOW – my question about the new mRNA flu shot is similar.
I could ask whether the flu vaccine’s “spike protein” (it’s called a “hemagglutinin glycoprotein”) also has a hall pass that gets it into the cell nucleus. I could even ask if the influenza HA glycoprotein also “escorts” its own mRNA into the nucleus, as does the COVID spike protein.
However, that requires experimentation. I can’t do that work.
OK – can I just ask if the mRNA flu shots contain the hall pass into the nucleus?
Well, it turns out that you can ask, but there’s not necessarily an answer.
I could not find the answer, so I asked Grok.
And I asked Grok a slightly less pointed version of the question, since I am perfectly capable of checking for nuclear translocation sequences myself, so that Grok would not detect “conspiracy theory thinking” on my part, and thereby not consign my question to the “talk down to this human” conga line of incomplete answers.
LINK: https://x.com/i/grok?conversation=2088464094655385678
Q: Is there a published mRNA sequence for the new mRNA flu vaccine, mFlusiva, from Moderna?
A: (from Grok)
No, there does not appear to be a publicly published full mRNA (nucleotide) sequence for Moderna’s mFlusiva (mRNA-1010).
mFlusiva is the FDA-approved (as of early August 2026) trivalent mRNA influenza vaccine for adults 50+ (traditional approval for ages 50–64; accelerated for 65+). Each 0.38 mL dose contains 37.5 µg total mRNA (12.5 µg each of three RNAs) encoding the full-length hemagglutinin (HA) glycoproteins of the season’s recommended strains (for the 2026–2027 formula: A/Missouri/11/2025 (H1N1)pdm09-like, A/Michigan/105/2025 [A/Darwin/1415/2025 (H3N2)-like], and B/Pennsylvania/19/2025 [B/Pennsylvania/14/2025-like]), formulated in lipid nanoparticles (SM-102, PEG2000-DMG, cholesterol, DSPC).
Public documents (prescribing information/DailyMed, FDA briefing documents and clinical review, Moderna product pages, and peer-reviewed trial publications) describe the composition, encoded antigens/strains, manufacturing process (in vitro transcription, no cells/eggs), and clinical data, but they do not disclose the actual nucleotide sequences of the mRNAs. These would include codon optimization, specific 5′/3′ UTRs, poly(A) tail, nucleoside modifications (typically N1-methylpseudouridine, as used in Moderna’s platform), and any stabilizing mutations (noted for the influenza B HA in non-surface-exposed regions).
- The underlying viral HA amino-acid (or genomic) sequences of the recommended strains are publicly available via databases such as GISAID or NCBI, as with any seasonal flu vaccine components.
- Moderna and related patents/publications disclose example or earlier-generation influenza mRNA constructs, sequences for other candidates, or general platform elements (e.g., UTRs used in some Moderna mRNAs), but not the proprietary, strain-updated commercial sequences for the approved mFlusiva product. patents.google.com
- This is consistent with how proprietary vaccine sequences (including prior Moderna mRNA products) are typically handled—they are not routinely released in full in labeling or regulatory summaries.
In short, while the antigens, doses, and high-level design are public, the exact published mRNA sequence for mFlusiva is not available. Any claims of a full sequence circulating would need independent verification against primary sources.
(END GROK)
(BEGIN WOLF)
First of all, just for the record, this is a great answer. Once again, thank you, Elon!
This situation seems a bit different from small-molecule drugs, where the exact molecules in the drug MUST be described in full, not only to the FDA, but to the public. Probably a feature that big pharma will eventually pay government to remove, but until then, something that certainly cramps their style.
Now, I was able to track things down a bit, and get CLOSE to the actual sequence for the vaccine, but I have been unable to find the exact sequence.
Here is what I did find.
(1) Link to full prescribing information.
(2) Information about ingredients
| MFLUSIVA influenza vaccine, mrna injection, suspension |
| Product Information Product Type VACCINE Item Code (Source) NDC:80777-500 Route of Administration INTRAMUSCULAR |
| Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength RNA-101-BFL3 (UNII: FPY755GU6Z) (RNA-101-BFL3 – UNII:FPY755GU6Z) RNA-101-BFL3 12.5 ug in 0.38 mL RNA-101-BFL6 (UNII: G35CN36JAP) (RNA-101-BFL6 – UNII:G35CN36JAP) RNA-101-BFL6 12.5 ug in 0.38 mL RNA-101-BFL5 (UNII: WAH8KM77XC) (RNA-101-BFL5 – UNII:WAH8KM77XC) RNA-101-BFL5 12.5 ug in 0.38 mL |
| Inactive Ingredients Ingredient Name Strength SM-102 (UNII: T7OBQ65G2I) 1,2-DIMYRISTOYL-RAC-GLYCERO-3-METHOXYPOLYETHYLENE GLYCOL 2000 (UNII: 9X2596CIE0) CHOLESTEROL (UNII: 97C5T2UQ7J) 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE (UNII: 043IPI2M0K) TROMETHAMINE (UNII: 023C2WHX2V) TROMETHAMINE HYDROCHLORIDE (UNII: 383V75M34E) SUCROSE (UNII: C151H8M554) WATER (UNII: 059QF0KO0R) |
(3) Selected information about mRNA ingredients
RNA-101-BFL3 (UNII: FPY755GU6Z)
RNA-101-BFL6 (UNII: G35CN36JAP)
RNA-101-BFL5 (UNII: WAH8KM77XC)
(4) UNII codes
FPY755GU6Z
G35CN36JAP
WAH8KM77XC
(5) Look up UNII codes
Website: https://precision.fda.gov/uniisearch
Results:
https://precision.fda.gov/uniisearch/srs/unii/FPY755GU6Z
https://precision.fda.gov/uniisearch/srs/unii/G35CN36JAP
https://precision.fda.gov/uniisearch/srs/unii/WAH8KM77XC
(6) CAS Registry Numbers and CAS Names
(a)
3115056-86-2
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza A (Missouri/11/2025 (A/H1N1))-like virus hemagglutinin codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL3), inner salt
(b)
3115056-85-1
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza A (Michigan/105/2025 (A/H3N2))-like virus hemagglutinin codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL5), inner salt
(c)
3118110-32-7
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza B/Victoria Pennsylvania/19/2025-like virus hemagglutinin [288-valine,381-tyrosine] codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL6), inner salt
That is as far as I could go. Registry numbers and names. Trying to look up the CAS registry numbers failed.

CAS Common Chemistry covers – well – common chemicals, including some surprisingly unusual ones, but it clearly doesn’t cover everything. For a lot of molecules – ones that are not “public figures” – one has to get behind the paywall by buying a product like SciFinder.
For example, CAS Common Chemistry has a page for one of the allegedly inactive substances in the vaccine – tromethamine.
LINK: https://commonchemistry.cas.org/detail?cas_rn=77-86-1&search=tromethamine
SIDEBAR: I’ll do a whole post about tromethamine later – it’s one of the best and most hilarious demonstrations of the (to borrow Scott’s verbiage) “weak, fake and gay” duplicity of the pharma-government-fincorp-media complex that I’ve ever seen. I’m personally glad they smartly added this compound to the clot shot, but to lie about why they did it – just so WEAK, FAKE AND GAY!
It is possible that the three names we retrieved above would allow trained biochemists to get very close to the actual sequences that were used, but in reality, to get the full, exact composition, including DNA contamination, we will almost certainly have to wait for independent researchers to analyze and sequence vials of the mFlusiva vaccine.
SO – in answer to the original question, we won’t truly know if there is either a public or secret access code to the cell nucleus in this vaccine, until somebody in free science actually analyzes the sequence of the vaccine, and somebody else actually checks and sees if the protein and/or the mRNA gets trafficked into the nucleus.
To borrow a saying from Nancy Pelosi, “We have to inject it, to find out what’s in it.”
Honestly, I think if Thomas Jefferson saw what patents have done to science, he would pull the whole idea up by the roots and figure out some other way to implement it. What that something else is, I don’t know. But what we have now is clearly problematic.
W

And remember…….
Until victory, have faith!

And trust the big plan, too!

And as always….

ENJOY THE SHOW

W











At the end of yesterday’s open, PAVACA brought the sad news of the death of actress Hayden Panettiere, age 36, due to likely cardiac arrest, and the usual suspects are already waving their hands and boarding up the windows at the funeral home with giant signs saying “IT WASN’T THE VAXX”. Apparently her 28-year-old brother died of a heart ailment right in the vaxx, too, so it’s looking doubly suspicious.
https://stateofthenation.info/?p=76957
Anyway, more news coming out here and there – I’ll add additional linxx.
https://www.tmz.com/2026/08/17/hayden-panettiere-found-dead-by-a-friend-inside-greenville-home/
https://www.tmz.com/2026/08/17/hayden-panettiere-death-narcan-found-in-condo/
Interesting comment on another TMZ clickbait article….
I find it increasingly difficult to have sympathy for the defenders of the ‘shots’. There’s a signpost up ahead in the distance. It reads: Beyond this point, you won’t care about the supporters of the shots or what happens to them.
Yeah, I hear you.
The second TMZ article says this:
Of course the vax is always a suspect, but no one thinks she could have overdosed? When I first read about her, in a different article, my impression was that she had had a troubled life and I wondered if it might have been suicide. We will probably see autopsy and toxicology results eventually. May she RIP.
Thank you for looking into it. The science is above my pay grade and I will not be taking the shot, but IMO the public needs to know this information, along with a basic explanation of why it’s important.
I have found a remarkable absence of curiosity about the question, except by the original author of the paper and a few people he knows. I think that, originally, the DNA contamination issue was a much simpler and logically complete explanation of why there was nuclear incorporation of vaccine sequences. There were more jumpable hoops that needed to be fully demonstrated for genomic uptake from mRNA to be proven.
But beyond that, I think people are just tired of proving that all the old lies were lies. The liars are just wearing us down.
Yes, the liars are wearing people down, but also, many who aren’t steeped in science don’t know enough to understand what questions to be asking or to know if answers they might be provided would be accurate or adequate.
THIS!!!
I’ve never seen this question asked, but it’s a good one.
There is no answer to that question which is acceptable to mainstream scientism.
This is probably happening in a lot of companies.
“I had to explain that the EEOC doesn’t currently accept the robot defense for federal civil rights violations.”
Ya think? 😂
You can bet little miss sunshine HR manager wouldn’t be so happy if the Ai was discriminating against women 😁
.
“She seemed genuinely confused and argued that the AI made the decision, not her, so we’re insulated from liability.”
Immediately blame-shifting and dodging any and all accountability, and then instinctively involving others (“we’re insulated from liability”) in her crime. Nice work!
“This is probably happening in a lot of companies.”
___________
Only all of them that are using Ai to screen applicants…
Sec. Sean Duffy:
The problem is not that no Americans want to buy an EV, the problem is that legacy auto makers can’t make an EV that anyone wants to buy. Which is hardly surprising, since they’re trying to make EVs the same way they make regular cars.
Tesla has the best selling car in the world, for three years straight.
Best selling, including EVs and gas cars, Tesla beats them all.
If they have the #1 selling car on earth, that means somebody wants to buy them.
…………………..
Brave Ai: The Tesla Model Y is the world’s best-selling passenger car for three consecutive years (2023, 2024, and 2025), beating all internal combustion, hybrid, and electric vehicles.
Tesla confirmed this status via its Chinese social media accounts, citing data from research firms including JATO Dynamics, Statista, and Focus2Move.
Key milestones include:
• Cumulative Sales: The Model Y has surpassed 4 million global units sold since its launch.
• 2023 Dominance: It became the first electric vehicle in history to claim the global #1 spot, outselling traditional leaders like the Toyota RAV4 and Corolla.
• Market Share: Despite a slight decline in annual sales volume from its 2023 peak of ~1.22 million units, the Model Y maintained its top position through 2025, capturing approximately 1.3-1.4% of the global auto market.
…………………..
The rich guy says he would stop working when he reached the $2 million mark, furlough his employees, and play golf and go fishing.
IMO, the issue that the Dems are hesitant to voice (yet) is that they want total control so that the rich would not be allowed autonomy of where to live, when to work, etc. The commie Left wants to get its hands on their money and to control all the populace.
It’s the same as with gun control. What they really want is no guns in the hands of the people, period; but that’s so unpopular and unconstitutional that they have to try to make gun ownership harder, piecemeal.
One point she makes is that they “look good”—hair implants and extensions, white and straight teeth, pedicures and manicures, tattoos, etc.
Back when people were posting videos of those who were upset about the new food stamp rules that required them to work a certain number of hours a week, I noticed that all the ones I saw had their nails done, rings on their fingers, makeup and hair done, etc.
She’s Tammy Pescatelli.
I’ve been thinking about how I might warn friends and family against the new flu vaccine, knowing that it’s probably pointless.
So I asked Grok, to find out what he would say, or what he is telling other people who might research the mRNA flu vaxx.
“Grok,
There is a new mRNA flu vaccine for this year, and many people are concerned about it from a health standpoint, for the same reasons many people have concerns about the mRNA covid vaccination and boosters.
At the same time, the mainstream media (and some people in government) make light of these concerns, even though as evidence keeps coming out (peer reviewed studies, congressional testimony, personal doctor testimony, doctors like Dr. Robert W. Malone and Dr. Steve Kirsch, Dr. Pete McCullough and many more), there appears to be a mountain of evidence for concern.
Many people have friends and family who blindly believe the mainstream media and get their vaccines.
There is so much information about the danger of mRNA vaccines that it’s hard to even know where to begin, in the effort to try to warn friends and family who are skeptics.
How would you put together a summary of the evidence (both recent and early) in a way that might persuade a skeptic to at least look at the evidence?”
.
Grok:
“The scientific consensus from large-scale trials, regulatory reviews, and population studies is that approved mRNA COVID-19 vaccines and the newly approved mRNA flu vaccine (Moderna’s mFLUSIVA/mRNA-1010) have favorable benefit-risk profiles for indicated groups, with known rare risks that are monitored and contextualized against disease risks.
Claims of a broad “mountain of evidence” for systemic danger from the doctors named (and similar sources) have not held up under scrutiny by major journals, regulators, or large independent datasets; some key papers have been retracted for unreliable conclusions and misrepresented data.
New mRNA flu vaccine (2026 data)
Moderna’s trivalent mRNA-1010 (mFLUSIVA) received FDA approval in August 2026 for adults ≥50 years (traditional approval for ages 50–64; accelerated approval for ≥65 with a required post-marketing effectiveness study). It is the first licensed seasonal mRNA flu vaccine in the US.
• Efficacy: In the phase 3 Fluent trial (~40,700 adults ≥50, published NEJM May 2026), RT-PCR-confirmed influenza-like illness occurred in 2.0% of mRNA-1010 recipients vs. 2.8% of standard-dose comparator recipients (relative vaccine efficacy 26.6%, 95% CI 16.7–35.4). Results were consistent in those ≥65 (rVE ~27%). It met noninferiority and superiority criteria versus standard-dose shots. Absolute difference was modest (~0.8 percentage points).
• Safety in the trial: Solicited reactions (injection-site pain, fatigue, headache, myalgia) were more common with the mRNA vaccine (e.g., pain 66% vs. 30%) but mostly mild-to-moderate and transient. Serious adverse events were similar (2.2% vs. 1.9%).
No myocarditis/pericarditis cases were identified in the predefined window. FDA reviewers and the VRBPAC panel (unanimous recommendation) noted higher reactogenicity, limited data in the frail/immunocompromised, single-season data, and questions about comparator choice in older adults, but concluded benefits outweighed risks.
Manufacturing speed is a practical advantage over traditional egg- or cell-based flu vaccines. Longer-term real-world data will accumulate post-approval, as with any new vaccine.
mRNA COVID-19 vaccines: accumulated evidenceHundreds of millions of doses have been given globally. Key findings from large, high-quality sources:
• Mortality and overall safety: A French national cohort of ~28 million adults aged 18–59 (median ~45 months follow-up through 2025) found vaccinated individuals had ~25% lower all-cause mortality and 74% lower risk of death from severe COVID-19 versus unvaccinated, with no signal of excess deaths from cancer, cardiovascular disease, or other major causes after adjustment. Sensitivity analyses supported this. Similar patterns appear in other long-term surveillance.
• Updated formulations: Studies of JN.1-containing and other recent boosters (e.g., Danish cohort of ~1.6 million) found no increased rates of 29 adverse events of special interest (including myocarditis, cardiac events, neurological events) in the 28-day window.
• Myocarditis/pericarditis (the most consistently documented rare risk): Highest after primary series doses in adolescent/young adult males (roughly 1–20+ excess cases per 100,000 in peak subgroups depending on dose, product, and study; lower with boosters and updated formulations). Risk is higher shortly after vaccination (especially dose 2) than background. Most cases are mild-to-moderate; long-term prognosis in vaccine-associated myocarditis appears better than conventional or COVID-infection-associated myocarditis in cohort data. COVID-19 infection itself carries a substantially higher risk of myocarditis and other cardiac complications. Regulators updated labeling with incidence estimates and MRI follow-up data.
• Other signals: Large studies and meta-analyses have not substantiated claims of widespread excess deaths, infertility, widespread autoimmune disease, cancer causation, or DNA contamination at levels causing harm. Residual DNA amounts fall within established limits; theoretical concerns have been addressed by regulators as implausible based on available evidence.
Context on dissenting voicesDoctors such as Robert Malone, Peter McCullough, and Steve Kirsch have raised concerns about spike protein effects, immune dysregulation, VAERS signals, trial data interpretation, and long-term risks. Some of their co-authored reviews have been retracted (e.g., a 2024 Cureus narrative review) because conclusions rested on unreliable or misrepresented citations and data.
Independent fact-checks and scientific critiques have found many specific numerical claims (e.g., vaccines causing more deaths than they prevent) inconsistent with trial re-analyses, pharmacovigilance, and population studies. VAERS is a passive reporting system useful for signal detection but not for establishing causation or rates without rigorous follow-up. These views remain minority positions relative to the body of evidence from regulatory agencies (FDA, EMA, etc.), CDC, WHO, and large independent cohorts.
How to discuss with skeptics productively
• Focus on primary sources rather than summaries or secondary commentary: the NEJM Fluent trial for the flu vaccine, the French JAMA Network Open mortality study, FDA labeling/briefing documents, and systematic reviews on myocarditis.
• Acknowledge real, labeled risks (reactogenicity; rare myocarditis, higher in young males after certain doses) and the limits of early data. Absolute risks matter: flu and COVID still cause substantial morbidity/mortality in older and high-risk groups.
• Compare risks to the diseases themselves and to alternative vaccines where data exist. Absolute risk reductions and number-needed-to-vaccinate versus number-needed-to-harm are more informative than relative figures alone.
• Note that higher short-term reactogenicity does not equal higher serious harm rates in the available trial and surveillance data.
• Encourage shared decision-making with a personal physician who knows the individual’s risk factors (age, comorbidities, prior reactions, current epidemiology).
Evidence evolves with more seasons of use and longer follow-up. For the new flu vaccine, post-marketing studies will be important. Official sources (FDA, CDC, published peer-reviewed trials in high-impact journals) remain the strongest place to start for anyone evaluating the data directly. Individual risk-benefit varies; the aggregate data do not support characterizing these vaccines as carrying the broad dangers sometimes claimed.”