Our mission, as God-fearing and God-loving patriots, is to defend this Constitutional Republic and to increase its greatness, in all good things and ways, by using our voices in free but courteous speech, by discussing the happenings of the world and coming to a profound understanding of those things, and by sharing and promulgating these Truths on both this platform and others.
This Stormwatch Monday Open Thread remains open – VERY OPEN – a place for everybody to post whatever they feel they would like to tell the White Hats, and the rest of the MAGA/KAG/KMAG world (with KMAG being a bit of both).
Our various sister sites, listed in the Blogroll in the sidebar
Our beloved country is STILL under DIRECT THREATS by hostile forces – notably COMMUNISTS – and they’re HERE IN AMERICA.
Daily outrage and commie phuckery still abound.
We can give in to despair…or we can be defiant and fight back in any way that we can.
Commies won’t win!
And we will keep saying COMMIES OUT until we get their FRAUD and INSANITY out of our country!
THE STUFF
Win the MAHA Front to Win the MAGA War
Recently, I had a bit of a revelation – followed by a much bigger one. The bigger revelation – the second one – is the title above. Specifically, it includes the MIDTERMS as a critical component.
We need to win on the MAHA front, to win the midterms. I’m not saying that MAHA is everything that wins the midterms. But I am saying that I believe MAHA victory is KEY to MAGA winning the midterms. And beyond.
Allow me to explain….
The First Revelation
At some point recently, I realized that the Democrats have seized on the idea of splitting MAHA against MAGA to weaken President Trump. They are seeking out natural contradictions between MAHA and MAGA, and looking for ways to turn the more liberal MAHA voters against President Trump.
scaring them on things like AI data centers
angering them on things like Epstein
disillusioning them on things like vaccines, RFKJ, etc.
playing to the racists and antisemites among them (this is orthogonal to MAHA, but is still depleting it)
And yet – ironically – we are making great strides on the MAHA front, if one simply looks at where we HAVE won battles. Yes, not everything is going our way RIGHT NOW, but seriously – we’re making a LOT of headway.
The Second Revelation
In my opinion, the Democrats and their allies in Big Harma, Bad Tech, and Cabal Finance, are barely hanging on in MAHA world – but they are using psy-ops and media mind control to convince us that we’re not winning. I’m not willing to go along with their bullshit.
In the last two or three years, I’ve stepped away from posting regularly about vaccines, medical technology, depop, and other MAHA topics, but I am being drawn back into the fight. Here is why.
We have had some great victories lately, from my scientific standpoint, but I feel that those victories are being underappreciated by MAHA. People are not seeing them. Each time, I realize just how “on the ropes” the Demmunists, the Faucists, the Weffen SS, and the Mandate Scumbags, really are.
I realize that if our side rallies around these MAHA victories, and push for more, we’re gonna CRUSH these criminals at the midterms.
I’m already seeing some recognition, on our side, of the “winnability” of this election by Trump and MAGA/MAHA in November. BUT – IMO – it’s not enough. It’s not as much as it should be.
Let’s just take a look at where things REALLY stand.
Fauci could have made a stand – but he didn’t. He pleaded the Fifth. This is a HUGE win for the forces of patients, real health, MAHA, and sanity.
Fauci’s top aide has pleaded guilty and is clearly cooperating with the DOJ on Fauci.
Fauci definitely committed federal money and ethics crimes, as called out by Josh Hawley in the Senate.
The mRNA flu vaccine is barely snaking by, and has demonstrated obviously and substantially lower safety than even the existing but still dubious traditional flu vaccines.
Even Grok admits that the mRNA flu vaccine is not a sound choice for vaccine-qualified patients in good health – and I believe that I can argue effectively that it’s not a good choice for MOST qualified but “should-be-contraindicated” patients.
CDC and FDA emails are TORCHING numerous villains of the Biden administration.
Top Slovakian academics were caught red-handed colluding with the mRNA vaccine industry to publish misleading science which knowingly minimized dangerous levels of DNA contamination in mRNA vaccines.
An impressive new theory liking alpha-gal syndrome to vaccines is not only fitting all the facts BETTER than pure tick-borne theories – it is explaining why Bill Gates doesn’t seem to mind those “boxes of ticks” accusations AT ALL. In fact – he may very well be BEHIND those misdirecting conspiracy theories.
The bottom line is that MAHA’s TRUTH-CENTERED SCIENCE is winning, and the MONEY SCIENCE that wants Trump gone yesterday is in big, big trouble. The other side is desperate, and doing desperate things.
And not only that – they are being swept away. We are changing the ecosystem.
I believe – strongly – that we can REFORM science in the next few years, if we (1) win the midterms, and (2) push to victory for MAHA during this election cycle.
But better still, I believe that if MAHA can WIN and SEE ITS OWN WINS during 2026, the winning of the midterms by MAGA is assured.
Republican presidential nominee former President Donald Trump shakes hands with Independent presidential candidate Robert F. Kennedy Jr. at a campaign rally at the Desert Diamond Arena, Friday, Aug. 23, 2024, in Glendale, Ariz. (AP Photo/Evan Vucci)
Thus, our task is to HELP MAHA WIN, and then to HELP MAHA SEE THE WINS.
I believe this site can be a VERY strong fighter in this cause.
There will be push-back – on many fronts. Some will be in this world. Some will be spiritual. We will contend with both. But we are positioned to help MAHA win, and MAHA’s win will insure that MAGA wins.
Please join me in this endeavor. Whether your support is spiritual, intellectual, moral or emotional, it is WELCOMED. Help to keep this site pure, God-loving, honest, friendly, welcoming, and free of unnecessary conflict (note that I did not say ALL conflict). Do what you think best – pitch in where you feel you can help.
There are 72 days until the election. Let’s make them count!
This DePat Tuesday Open Thread honors the author of the original Tuesday open thread on this site, namely the late Susie Sampson, a.k.a. Deplorable Patriot, among her other handles, pen names, etc.
For more on the untimely passing of Dear DePat, please see these three posts.
At one time, DePat handled FOUR daily open threads here, in addition to taking care of her relatives, choir duties, and numerous other responsibilities. She was a powerhouse – a dynamo – a true force of nature.
DePat’s faith in Trump, Q, “The Plan”, the White Hats, and “the anons” in general, was legendary. Although I didn’t always agree with her quick acceptance of some sketchier evidence and fringier theories, I will gladly admit to “coming around” to numerous so-called “conspiracy theories” which she championed first. I was always careful to give her credit for being right, too, when I had been wrong.
It is impossible to overstate how much DePat did for not only this site, but for her country. I urge all to say a quick prayer of thanks, whenever you think of her, for the privilege of knowing, in life or after death, such an exemplary human being, and lover of God.
And thank you, Susie, for the firm foundation which you left us, when you were called to your true home!
Is There Another Cell Nucleus Hall Pass in the New mRNA Flu Vaccine, mFlusiva?
Let’s start off with some history.
Are you aware of the fact that both the Moderna AND the Pfizer COVID vaccines contained a genetic sequence that acts like a “hall pass” or “VIP ticket”, allowing the holder to get into the nucleus of human cells?
Were it not for somebody dropping a link to an obscure paper in my Twitter timeline back in early 2023, I would have never realized how extra sketchy that made both the virus and the vaccines – and especially the latter, since it would have been theoretically possible to remove the nuclear hall pass from the spike protein used as the vaccine.
Let me repeat that. They left the “hall pass” in the mRNA code for the vaccine.
But – and I have to stress this – it was not just that this “hall pass” was there. No. It was much worse. The paper in question was experimental, and it showed that the viral spike protein not only contained the hall pass, but that it WORKED. The hall pass actually worked to get the spike protein into the nucleus. They even had PICTURES of it in the nucleus.
The hall pass not only got the spike protein into the nucleus – the spike protein THEN got the mRNA that coded for it into the nucleus, as well.
Yes. You are reading that correctly. The spike protein of SARS-CoV-2 has a known sequence in it that ends up getting both IT and the mRNA that created it, into the cell nucleus.
One would THINK that this might be a big deal. Especially after we were REASSURED that NO, VIRGINIA – THE mRNA WILL NEVER, EVER GET INTO THE CELL NUCLEUS, YOU FOOLISH VACCINE SKEPTICS.
Are you seeing why this is kind of a big deal?
SO – NOW – my question about the new mRNA flu shot is similar.
I could ask whether the flu vaccine’s “spike protein” (it’s called a “hemagglutinin glycoprotein”) also has a hall pass that gets it into the cell nucleus. I could even ask if the influenza HA glycoprotein also “escorts” its own mRNA into the nucleus, as does the COVID spike protein.
However, that requires experimentation. I can’t do that work.
OK – can I just ask if the mRNA flu shots contain the hall pass into the nucleus?
Well, it turns out that you can ask, but there’s not necessarily an answer.
I could not find the answer, so I asked Grok.
And I asked Grok a slightly less pointed version of the question, since I am perfectly capable of checking for nuclear translocation sequences myself, so that Grok would not detect “conspiracy theory thinking” on my part, and thereby not consign my question to the “talk down to this human” conga line of incomplete answers.
Q: Is there a published mRNA sequence for the new mRNA flu vaccine, mFlusiva, from Moderna?
A: (from Grok)
No, there does not appear to be a publicly published full mRNA (nucleotide) sequence for Moderna’s mFlusiva (mRNA-1010).
mFlusiva is the FDA-approved (as of early August 2026) trivalent mRNA influenza vaccine for adults 50+ (traditional approval for ages 50–64; accelerated for 65+). Each 0.38 mL dose contains 37.5 µg total mRNA (12.5 µg each of three RNAs) encoding the full-length hemagglutinin (HA) glycoproteins of the season’s recommended strains (for the 2026–2027 formula: A/Missouri/11/2025 (H1N1)pdm09-like, A/Michigan/105/2025 [A/Darwin/1415/2025 (H3N2)-like], and B/Pennsylvania/19/2025 [B/Pennsylvania/14/2025-like]), formulated in lipid nanoparticles (SM-102, PEG2000-DMG, cholesterol, DSPC).
Public documents (prescribing information/DailyMed, FDA briefing documents and clinical review, Moderna product pages, and peer-reviewed trial publications) describe the composition, encoded antigens/strains, manufacturing process (in vitro transcription, no cells/eggs), and clinical data, but they do not disclose the actual nucleotide sequences of the mRNAs. These would include codon optimization, specific 5′/3′ UTRs, poly(A) tail, nucleoside modifications (typically N1-methylpseudouridine, as used in Moderna’s platform), and any stabilizing mutations (noted for the influenza B HA in non-surface-exposed regions).
The underlying viral HA amino-acid (or genomic) sequences of the recommended strains are publicly available via databases such as GISAID or NCBI, as with any seasonal flu vaccine components.
Moderna and related patents/publications disclose example or earlier-generation influenza mRNA constructs, sequences for other candidates, or general platform elements (e.g., UTRs used in some Moderna mRNAs), but not the proprietary, strain-updated commercial sequences for the approved mFlusiva product. patents.google.com
This is consistent with how proprietary vaccine sequences (including prior Moderna mRNA products) are typically handled—they are not routinely released in full in labeling or regulatory summaries.
In short, while the antigens, doses, and high-level design are public, the exact published mRNA sequence for mFlusiva is not available. Any claims of a full sequence circulating would need independent verification against primary sources.
(END GROK)
(BEGIN WOLF)
First of all, just for the record, this is a great answer. Once again, thank you, Elon!
This situation seems a bit different from small-molecule drugs, where the exact molecules in the drug MUST be described in full, not only to the FDA, but to the public. Probably a feature that big pharma will eventually pay government to remove, but until then, something that certainly cramps their style.
Now, I was able to track things down a bit, and get CLOSE to the actual sequence for the vaccine, but I have been unable to find the exact sequence.
Product Information Product Type VACCINE Item Code (Source) NDC:80777-500 Route of Administration INTRAMUSCULAR
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength RNA-101-BFL3 (UNII: FPY755GU6Z) (RNA-101-BFL3 – UNII:FPY755GU6Z) RNA-101-BFL3 12.5 ug in 0.38 mL RNA-101-BFL6 (UNII: G35CN36JAP) (RNA-101-BFL6 – UNII:G35CN36JAP) RNA-101-BFL6 12.5 ug in 0.38 mL RNA-101-BFL5 (UNII: WAH8KM77XC) (RNA-101-BFL5 – UNII:WAH8KM77XC) RNA-101-BFL5 12.5 ug in 0.38 mL
3115056-86-2 RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza A (Missouri/11/2025 (A/H1N1))-like virus hemagglutinin codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL3), inner salt
(b)
3115056-85-1 RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza A (Michigan/105/2025 (A/H3N2))-like virus hemagglutinin codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL5), inner salt
(c)
3118110-32-7 RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted influenza B/Victoria Pennsylvania/19/2025-like virus hemagglutinin [288-valine,381-tyrosine] codon-optimized transgene plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger RNA-101-BFL6), inner salt
That is as far as I could go. Registry numbers and names. Trying to look up the CAS registry numbers failed.
CAS Common Chemistry covers – well – common chemicals, including some surprisingly unusual ones, but it clearly doesn’t cover everything. For a lot of molecules – ones that are not “public figures” – one has to get behind the paywall by buying a product like SciFinder.
For example, CAS Common Chemistry has a page for one of the allegedly inactive substances in the vaccine – tromethamine.
SIDEBAR: I’ll do a whole post about tromethamine later – it’s one of the best and most hilarious demonstrations of the (to borrow Scott’s verbiage) “weak, fake and gay” duplicity of the pharma-government-fincorp-media complex that I’ve ever seen. I’m personally glad they smartly added this compound to the clot shot, but to lie about why they did it – just so WEAK, FAKE AND GAY!
It is possible that the three names we retrieved above would allow trained biochemists to get very close to the actual sequences that were used, but in reality, to get the full, exact composition, including DNA contamination, we will almost certainly have to wait for independent researchers to analyze and sequence vials of the mFlusiva vaccine.
SO – in answer to the original question, we won’t truly know if there is either a public or secret access code to the cell nucleus in this vaccine, until somebody in free science actually analyzes the sequence of the vaccine, and somebody else actually checks and sees if the protein and/or the mRNA gets trafficked into the nucleus.
To borrow a saying from Nancy Pelosi, “We have to inject it, to find out what’s in it.”
Honestly, I think if Thomas Jefferson saw what patents have done to science, he would pull the whole idea up by the roots and figure out some other way to implement it. What that something else is, I don’t know. But what we have now is clearly problematic.
This Stormwatch Monday Open Thread remains open – VERY OPEN – a place for everybody to post whatever they feel they would like to tell the White Hats, and the rest of the MAGA/KAG/KMAG world (with KMAG being a bit of both).
Our various sister sites, listed in the Blogroll in the sidebar
Our beloved country is STILL under DIRECT THREATS by hostile forces – notably COMMUNISTS – and they’re HERE IN AMERICA.
Daily outrage and commie phuckery still abound.
We can give in to despair…or we can be defiant and fight back in any way that we can.
Commies won’t win!
And we will keep saying COMMIES OUT until we get their FRAUD and INSANITY out of our country!
THE STUFF
Let’s Talk About Virus, Vaccine, and Protein Shedding
I have noticed something very interesting about the “shedding” phenomenon.
The “vaxxes can do no wrong” side doesn’t like to talk about shedding. They don’t bring shedding up, and they frequently change the subject when an argument about shedding gets started.
It’s easy to dismiss “shedding” as a conspiracy theory, but once one sees actual Pfizer documentation on the topic (link now dead, curiously), the reality of “shedding” in the vaccine world hits one square in the face. Media shills for vaccines may be crowing on TV that “shedding” is all a big lie, but when the vaccine manufacturer is testing the vaccine, suddenly it’s the greatest danger of the study, and test participants find themselves separated if not isolated from spouses, infants, relatives and friends. Yet another reason people cannot stand the lying fake news media.
The most disingenuous current deflection of the problem in vaccines, is that the FDA has a HUGE concern with the shedding of “gene therapy” products – which often use mRNA in lipid nanoparticles – but then says that it’s not a problem in mRNA vaccines because they’re not classified as gene therapy products. Robert Malone has always been highly critical of this teenager-level dodge of responsibility, and frankly I think anybody involved in that scandal needs to be fired from government and possibly prosecuted for fraud. It’s the same weak chutzpah as the 17-year-old murderer of his parents, demanding first leniency as an orphan, and then prosecution as a juvenile, when the initial lunacy doesn’t prevail.
I recall the first time I read documentation of how shedding of a vaccine was to be guarded against in a major vaccine clinical trial, by significant restrictions of the participants from close contact with other people during the observation period.
Shedding of a virus – why – that’s just DISEASE. Communicable disease. We are all familiar with THAT.
Well, vaccines can be a virus – including weakened and incompletely deactivated viruses. It can even be a normal but less pathogenic virus, like cowpox, used as a literal vaccine against a more dangerous virus like smallpox. A weak but “live” virus may be difficult to transmit, but in many cases, transmission is still possible.
Shedding of a virus per se is the most potentially dangerous form of shedding, but it’s also the most well-known, and the easiest to understand. A limited number of viral particles is all that is necessary to start a disease in a new host. Being a victim of viral shedding is literally catching a disease. This is reality – something that happens all the time with common colds and influenza-like diseases (ILIs). Catching a shed virus is vaccination against catching the exact same form again – but not against sufficiently mutated forms. We are familiar with THAT from COVID-19.
So when people catch a communicable viral disease, they catch a shed virus, start constructing the virus, and then shed the virus again. Simple, and very real. But the outcome of viral infection is very uncertain, and that unpredictability ends up being a liability of using sheddable viruses as vaccines.
There is a reason I’m harping on this form of shedding. One needs to keep shedding of vaccine in perspective with the more dangerous, more likely, and more consequential shedding of virus. If you suddenly experience symptoms of a disease, including symptoms of the protein produced by that disease, then it is far more likely that you are a victim of shedding of the actual virus, than shedding of the vaccine. This is a simple reality, which I believe has led many patriots, including Deplorable Patriot, astray, in losing focus on relative risks. It is important to keep ALL forms of shedding in mind.
Shedding of Proteins
At the other end of danger, is the shedding of viral proteins, but not the virus itself. Let’s consider that.
Viral proteins can’t reproduce, but they CAN show all the bad properties of other nasty, dangerous, pathogenic proteins.
For example, the spike proteins of corona viruses are notoriously pathogenic, and when they are administered to test animals in an aerosol, they create immediate pulmonary disease, and can even kill the test animals. Yes, it’s shocking.
Still not convinced that a small amount of “shed” protein can be dangerous? Let’s talk about snake venoms.
Snake venoms are mostly dangerous because of pathogenic proteins, and these proteins are often very similar to bacterial or viral proteins, or arthropod venoms, as well as powerful digestive enzymes.
The thing is – and you likely didn’t know this – venomous snakes “shed” not only their skin, but also their VENOM. That fact is why people who care for venomous reptiles need to wear gloves and respirators when they clean cages. Shake venom gets into the cage dust, and cleaning it out exposes workers to skin and respiratory dangers pretty much like test animals breathing corona virus spike proteins in an aerosol.
So, again, shedding of pathogenic proteins can be real.
The only questions are, what viral protein is it, how is one being exposed to it, and how much of it is one being exposed to.
I’ve discussed this in the past, when we talked about the possibility of shed spike protein having the potency to cause symptoms in a person being shed upon. You can refresh yourself with the discussion in the following post and other linked posts here.
How much exposure to pathogenic protein is allowable? That is a HUGE question – and between the extremes of total neglect and total fear, lies something called “exposure and immunity”. Including “natural immunity”. We’ll return to that topic later.
Shedding of Vaccines
In between the shedding of intact viruses, and the shedding of viral proteins, lies an intermediate possibility – the shedding of what in nature are called “virus-like particles”, or what in medicine are called “lipid nanoparticles”.
These are mRNA or DNA enclosed in something like a lipid nanoparticle, or the outer shell of a different virus.
These are, bluntly, mRNA vaccines.
In terms of both danger and safety, lipid nanoparticle vaccines are intermediate between live viral vaccines (always dangerous, IMO) and protein vaccines (least dangerous, IMO). Why is this? Well, bluntly, viruses propagate as a chain reaction, and have very little control over outcome. In contrast, a metered amount of a dead protein has great control over the outcome. mRNA vaccines are in between. They don’t reproduce, but they do create a greater but unpredictable amount of viral protein.
Pierre Kory has a very nice article about vaccine shedding, which I invite you to read.
By the time you finish that, you will understand that there is some need to address this issue now.
As a bit of an aside, you should note that Cory is AGAINST the use of nicotine patches for treatment of spike protein toxicosis, believing (as I do) that it probably has far more risks than benefits. This is highly relevant for DePat’s case.
Technical Approaches to Prevention of Shedding Injury
It is my belief that any good method to deal with both mRNA vaccine shedding and corresponding protein shedding should have the following characteristics.
Prevention is preferred to treatment
Treatment can be separate from prevention
Earlier is better for both prevention and treatment
Vaccine is more dangerous than protein, and is thus a priority
The final point needs some explanation.
While the protein can be dangerous at high enough levels, one of the greatest dangers of the vaccine is that it produces large quantities of the protein, and is thus automatically orders of magnitude more dangerous than the protein alone. This is not even considering the dangers of the mRNA technology itself.
Destroy the mRNA vaccine, and there is no protein made, nor any mRNA mechanism allowed to function badly.
Thus, targeting the shed vaccine FIRST makes sense.
THAT makes things easy, because the vaccine can be destroyed easily, provided that it has not yet entered the body.
The mRNA vaccines utilize lipid nanoparticles (a.k.a. liposomes) to enter cells. While these little particles are exceedingly dangerous at a cellular level, they have an intrinsic weakness – their easy destructibility by surfactants – meaning soaps and other cleaning agents.
I posed a research question to Grok, regarding this approach, and got a VERY satisfactory answer.
THE QUESTION
Grok, please give me a list of substances (ranging from specific chemical compounds to branded products) that are known to rapidly disrupt, break up, absorb, and/or inactivate liposomes, including liposomes that are referred to in the mainstream press as “lipid nanoparticles”. I am interested in both surface treatments (cleaning agents, topical medicines, skin washes, soaps, lotions, etc.) as well as things which can be taken internally (oral or injectable), as medicines, that are more specific for disrupting liposomes in the bloodstream, for example as an antidote to an inappropriately administered lipid nanoparticle vaccine, e.g., given mistakenly to an allergic patient.
THE ANSWER
BEGIN GROK
Surfactants/detergents (most effective and commonly documented disruptors of liposomes and lipid nanoparticles/LNPs), organic solvents, cyclodextrins, and certain other agents can solubilize or destabilize lipid bilayers. These work primarily by intercalating into the bilayer, extracting lipids/cholesterol, forming mixed micelles, or increasing permeability/leakage until the vesicle structure collapses. Effects are concentration-, composition-, and condition-dependent (lipid type, cholesterol content, PEG coating, temperature, pH, etc.). LNPs used in mRNA vaccines share similar phospholipid/cholesterol/PEG-lipid components and are susceptible in vitro to the same classes of agents. pubs.acs.org +2
There is no established, safe, specific medical antidote that rapidly and selectively disrupts circulating LNPs (e.g., after mistaken administration of an mRNA vaccine to an allergic patient). LNPs are designed to be temporary and are cleared primarily via the mononuclear phagocyte system (liver/spleen), with natural degradation of the lipids. Systemic attempts to force rapid disruption with the agents below would generally be highly toxic (hemolysis, cell membrane damage, organ injury) and are not clinically used or recommended for this purpose. Allergic/anaphylactic reactions are managed with standard emergency care (epinephrine, antihistamines, corticosteroids, supportive measures), not LNP disruption.
Surface treatments / topical / cleaning agentsThese are relevant for cleaning residues, skin washes, or external inactivation:
Anionic, nonionic, and other surfactants/detergents: Sodium dodecyl sulfate (SDS/SLS), Triton X-100, Tween 20 (polysorbate 20), Brij surfactants, Zwittergent 3-14, quaternary ammonium compounds, and commercial soaps/detergents containing these. They saturate bilayers then convert liposomes/LNPs into mixed micelles. Used in lab assays (e.g., RiboGreen for mRNA release from LNPs) and industrial cleaning of LNP residues. Alkaline formulated detergents (e.g., potassium hydroxide-based) are effective for equipment cleaning of LNP residues at elevated temperature/contact time. pharmtech.com +2
Bile salts (sodium cholate, deoxycholate, taurocholate, etc.): Strong solubilizers of phospholipid bilayers; well-studied for vesicle-to-micelle transitions. Present in some digestive/intestinal contexts and used experimentally.
Alcohols and organic solvents: Ethanol, isopropanol, methanol (typically high concentrations). Disrupt hydrophobic interactions; improve solubility of lipids for cleaning but raise flammability/handling issues. pharmtech.com
Cyclodextrins (especially methylated or randomly methylated β-cyclodextrin / RAMEB / DMe-β-CD, and to varying degrees α-, β-, HP-β-CD): Extract cholesterol and phospholipids from membranes, increasing permeability, leakage, or causing collapse at sufficient concentrations. Effects depend on CD type, dose, and membrane cholesterol content. link.springer.com +2
Other noted factors: High concentrations of certain kosmotropic salts (e.g., ammonium sulfate) can aggregate/precipitate PEGylated liposomes; extreme pH, heat, or oxidation can destabilize; some nanoparticles or polymers can tear or fragment membranes under specific conditions.
Branded/consumer products that contain the above (many soaps, dish detergents, hand washes, some lotions or topical cleansers with surfactants/alcohols) can disrupt lipid structures on surfaces. Efficacy varies widely with formulation and contact conditions.
Internal (oral or injectable) agents
The same surfactants, bile salts, solvents, and high-dose cyclodextrins that work in vitro or on surfaces are generally not safe or selective for bloodstream use against LNPs. They disrupt host cell membranes (including red blood cells) at effective concentrations.
Bile salts occur physiologically in the intestine and can destabilize orally administered liposomes, but systemic (bloodstream) levels for intentional LNP disruption are not a therapeutic approach.
Cyclodextrins have pharmaceutical uses (e.g., solubilizing agents) and can interact with membranes, but high systemic doses for rapid LNP inactivation are not established as safe or effective antidotes and carry risks.
No specific medicines or injectables are approved or routinely described as LNP-disrupting antidotes for vaccine mishaps. Research on LNP fate focuses on clearance, protein corona, MPS uptake, and formulation stability rather than forced rapid inactivation in blood. nature.com
Important caveats: Literature on disruption is largely from in vitro biophysics, pharmaceutical formulation/stability studies, cleaning validation, or drug-delivery research—not clinical antidote development for circulating LNPs. “Rapid” disruption typically requires relatively high local concentrations of surfactant relative to lipid. PEG coatings or cholesterol content can modulate stability. Self-experimentation or off-label use of detergents, solvents, or high-dose agents internally is dangerous and not supported.
For any real-world allergic reaction or medical concern involving a vaccine or LNP product, seek immediate professional medical care; do not attempt chemical disruption. If this is related to laboratory work, cleaning protocols, or formulation science, consult primary literature or specialists for concentration- and condition-specific details.
END GROK
Let me translate all of that.
As long as the shed vaccine is still on the surface of your skin, on clothing, on a mask, or on a surface in your house, the vaccine can be destroyed by all sorts of cleaning products, including surfactants, soaps of all kinds, alcohols, oxidizing agents, bile salts, cyclodextrins, and probably anything useful for cleaning.
Further, any lotions or surface treatments which do not aid in skin penetration (like DMSO), but which do sweep things away from direct contact with your cells, are likely to be helpful in delaying, dissolving, and degrading lipid nanoparticles. Imagine spilled chemical on your skin – it’s the same principle. Diluting the vaccine and/or washing it off make sense.
It is a much different story once a lipid nanoparticle vaccine is inside you – be that from prolonged skin contact, breathing, swallowing, or any other route into your body (like the mRNA jab). None of these things work, once the vaccine is inside you, or in the bloodstream. In fact, these cleaning agents are just as dangerous to your internal cellular machinery (lipid-coated droplets) as they are to the lipid nanoparticles. However, as long as the shed vaccine doesn’t get into your bloodstream (a lower probability than a surface reaction), you don’t have to worry as much about that, as about vaccine damage to skin or mucus membranes where shed vaccine made contact.
Thus, the best time to fight shedding, IMO, is soon after contact. Washing, application of lotions or alcohols, etc., should inactivate shed vaccine. Washing away or denaturing shed protein is also likely to work at the same time.
Again, it is important to remember is that systemic problems from shedding are much less likely than surface problems.
A Realistic Program Against Shedding
This is my opinion. Others may differ. That’s OK. I am just offering my perspective. YMMV.
My first concern remains shedding of virus.
If I am not accepting the trade-offs of the vaccine itself, then my protection is my immune system. My immune system has worked very nicely over the years, against colds, flu, and flu-like illnesses, including all forms of COVID as well as non-COVID coronaviruses. There are appropriately long gaps between infections, and the infections (except for OG Wuhan) have not been debilitating, indicating a functioning immune system.
My immune system is always supplemented with plenty of vitamin D, because vitamin D levels are extremely highly correlated with immunity to viruses. The relationship is stark, and backed by the strongest science. Rates of viral infections almost disappear at high serum levels of vitamin D. There are probable mechanisms for this, but I literally don’t care what they are. Without knowing the causation, the correlation still works. I cannot recommend vitamin D enough. You need to be supplementing it, and maintaining maximum exposure to sunlight. Better still, a measurement of serum levels, but it’s not cheap and your doctor likely won’t recommend it.
Doesn’t matter. Supplementation is cheap and easy and not dangerous, so why not just make sure you are taking a few thousand IUs daily? Just do it. When you notice an appropriately long time between colds and flu, you know you’re taking enough.
Likewise, I make sure that I am not deficient in any vitamin or mineral. Vitamin C, magnesium, selenium and zinc are very important.
However, THIS is even more important.
Avoiding crowded events is critical to reducing exposure to shed viruses. I can link almost every case of influenza or coronavirus infection in recent years to a specific event where there were lots of people crowded together.
In other words, shedding. Viral shedding. As in, viral shedding by people in close proximity.
Thus, avoid crowded public events, particularly in the wintertime, when viruses are maximally spread.
After viral shedding, my next concern is vaccine shedding.
IMO casual vaccine shedding from strangers in momentary close proximity, but not direct physical contact, is far, far less of a problem than living with a vaxxed person for that week after vaccination. Even worse, sleeping with that person who just had a vax.
You should note that my concerns here are EXACTLY what the pharmaceutical industry is concerned about in vaccine trials. That includes live virus AND gene therapy products (even if they don’t call them gene therapy products).
My recommendation is to avoid close contact with vaxxed people for at least 2 days after vaccination, and better a full week. Two weeks should be more than enough, always.
Why? Because the vaccine itself degrades. Even if a person take the vaccine, and shows all sorts of disease symptoms for weeks if not months (please pray for them if this is the case) due to vax-initiated protein production that won’t shut off, they are unable to transmit the vaccine to you, because it is no longer there. The vaccine is degraded, but protein production may still be running.
What about shed vaccine when we can’t avoid being around an individual?
This is when to use soaps, alcohol-based gels, and other skin products. This is when to wash your hands after that oily, wet handshake from some just-jabbed joker, sweating profusely due to their mRNA jab. This is when to stand back from people who can’t “say it” without the need to “spray it”. And note that all of this works even better for VIRUS.
IMO, the vaccine is a far greater danger to you, than the protein these poor victims are now producing. YOU don’t want to be inappropriately producing the protein.
And HERE is where my opinion is likely to differ with yours.
My final concern, about exposure to environmental viral protein, is largely not a concern.
Why? Because this is the natural way in which we build immunity.
Even against a bioweapon. I repeat. Even against a bioweapon – as either a virus or a vaccine.
I literally don’t care if the neighbor sheds small amounts of spike protein or flu proteins on me, because THAT is the vaccination that I prefer – the one for which I am designed. Likewise, I am unconcerned with exposure to dead virus, because THAT is basically how we are naturally prepared for exposure to live virus.
Do I want to inject a protein or dead virus vaccine into me? Maybe – but more likely not. I am now very cautious about vaccines, given that I have lost much trust in the current “vaccine cult” in science. I still trust God and His natural evolutionary reality, however, so I am far more likely to simply trust a combination of pre-exposure of my healthy immune system to proteins, followed by full natural immunity from a well-tolerated episode of the disease.
Rabies? That’s a different story. I’ll take the vaxx, as long as it’s not mRNA. I’ve already done so, once before. I would ONLY take an mRNA rabies vaccine if the animal was confirmed to be rabid, because then it’s a “lesser of two confirmed evils” situation.
I am not going to get pregnant any time soon, and I’ve already had COVID and influenza several times each, so I’m not terribly concerned about exposure to proteins from new variants. In fact, I am at the point of “keeping up” with the latest versions.
SO – some jabbie wants to expose me to the latest spike protein in a non-infective way? Please! Not a problem. Go right ahead. Flu proteins? Be my guest. But I won’t let them expose me to the Soviet Trabant two-stroke mRNA vaccine which I very intentionally decided NOT to take.
And again, my final point. Even if the vaccine AND the protein it produces are “bioweapons” – guess what? I want to be immune to it. I want my system to adapt to its presence. I want natural immunity to all this shit – whether it’s purely “old natural” or “the new natural” that includes stupid human gain-of-function scientific error.
Do you see what I’m saying? GOD has this situation – ALREADY. Let go and let God – just do it at the right time and place.
I hope this helps. If you have questions, feel free to ask.
We have created this site as a place for people to openly express their thoughts and opinions. This is a place where honest but civil discussion of all topics is encouraged. This particular thread is – for the moment – TRUST THE PLAN Thursday. You are welcome to say what you think, in a civil and courteous manner that loves your neighbor. Free speech matters! Courteous speech makes it happen.
Please label all AI-generated content as being such, unless it is patently obvious (e.g., humorous AI images). It is important that we as individuals not begin to pretend that socially derived artificial intelligence is actually our own, as this form of stealthy social information averaging and feedback would be one more pretense and deception between people, in service of stupid Marxist socialism, and of those who wish to substitute their communally protected lies for actual truth.
You are you. AI is AI. Keep your identity. Don’t “Borg Out” on us!
And yes, it’s THURSDAY…again.
That was stolen from Wheatie.
Let’s steal her rules, too.
No food fights.
No running with scissors.
If you bring snacks, bring enough for everyone.
Other rules may be derivable from these, and that conjecture is left for discussion.
I decided that I would dump a dozen of my tabs once again. It’s cathartic. A few thoughts go out with each one.
(1) An old Wheatie post, from September 14, 2019, when this site was just shy of 1 year old. We were still on WordPress, and COVID had probably just been leaked from the Wuhan lab.
(2) An old Steve post, from the Qth of July, 2021, in the midst of COVID vaccination, when Steve covered Einstein’s early, revolutionary papers, laying foundations in both relativity and quantum mechanics.
(3) My 250th Anniversary thank you post, featuring Q = Quantum and a salute to our fallen patriots, in case you want to bookmark it. Also the finale on the Thursday posts with the Genesis stained glass artwork.
(4) A great video on Trump’s Main Street / Golden Age / reindustrialization strategy. Thanks to Duchess for bringing this to my attention.
(5) One of the best explanations of the Schroedinger equation – an intuitive physical and mathematical rationalization of how quantum mechanics arises out of classical physics.
(6) AI slop and eye-roll clickbait about Pluto is very interesting nonetheless. Much of this stuff is worth knowing. If you make it past the first repetitive, yawn-inducing, “delay of story” filler nonsense, it gets better!
(7) These two tabs go together. Think long and hard before you get an mRNA vaccine.
I wanted to let everyone know that my husband @DanVanAckeren1 took his own life on Friday, July 24, 2026. He was suffering for 5 years after the COVID-19 Pfizer vax gave him Multiple System Atrophy & other conditions. His was the 3rd suicide this week. My fight isn’t over. pic.twitter.com/iDGPNNKQo9
When you read about his case, you’ll understand that his life was a living hell. Please don’t roll the dice. Don’t trust these demons! They won’t have the mercy to just kill you – they will torment you until you kill yourself.
(8) Here’s an interesting argument leaning on the First Amendment – that restrictions on drug advertising would enable restrictions on energy advertising.
STEVE MILLOY: Banning Drug Ads Today Could Muzzle Energy Tomorrow
(9) Good habits are effective in helping people to NOT GET a nasty parasite in Hawaii, and those habits will serve you well here in the Great 48. Read about how to prevent rat lungworm brain infections, because that information will help keep you from getting other diseases here in REAL AMERICA.
(10) Horrible clickbait about fire ants is really an interesting ecology study about “horny toads” in Texas. Go ahead and click. Yeah, it’s AI slop, but it’s not terrible.
I will be hitting VERY HARD on the topic of mRNA vaccines in general, and the mRNA flu shot mFlusiva in particular, over the next few weeks.
I will be refreshing your memories to get you all back into FIGHTING SHAPE.
To begin with, I strongly suggest watching this 1 HOUR movie about mRNA vaccines. The main reason is that it will AWAKEN your dormant memories of the world under COVID. Automatic brain boost for our purposes.
I also think it is very important to see interviews with actual vaccine-injured people.
This movie will show you the reality of vaccine injury.
Thank you for your attention to this matter.
W
THE MOVIE:
Chapters:
00:00 Intro 02:53 Surgeon Joel Wallskog’s health issues 06:21 Operation Warp Speed initiative 06:38 Former CDC Director on mRNA vaccines 07:35 Regulators’ safety assessment 08:09 Calls to pause mRNA vaccines 09:32 mRNA researcher Robert Malone 12:56 Pathologist Ryan Cole on COVID vaccination 14:14 Cardiologist Aseem Malhotra on heart health 14:37 Cardiologist Peter McCullough on side effects 17:28 Scientist Jessica Rose on vaccine concerns 18:41 Critical care specialist Paul Marik on patient community 21:17 Explaining mRNA 23:45 How mRNA vaccines work 27:06 Spike protein and possible effects 30:57 Pathologist Arne Burkhardt’s biopsy findings 32:49 Health agencies’ safety stance 33:38 Vaccination in pregnancy and children 34:22 Artist Jessica Sutta’s health issues 39:03 Future uses of mRNA technology 42:55 Tobie Vergara’s health issues 45:12 History of mRNA vaccines 46:44 Modified mRNA technology 48:40 mRNA research status in 2017 49:07 Toxicity concerns in 2017 49:33 Progress in mRNA technology 49:50 mRNA vaccines during the pandemic 55:41 Support for post-vaccination syndrome 57:06 Doctors offering assistance Sources, studies, timecodes: https://docs.google.com/spreadsheets/…
This DePat Tuesday Open Thread honors the author of the original Tuesday open thread on this site, namely the late Susie Sampson, a.k.a. Deplorable Patriot, among her other handles, pen names, etc.
For more on the untimely passing of Dear DePat, please see these three posts.
At one time, DePat handled FOUR daily open threads here, in addition to taking care of her relatives, choir duties, and numerous other responsibilities. She was a powerhouse – a dynamo – a true force of nature.
DePat’s faith in Trump, Q, “The Plan”, the White Hats, and “the anons” in general, was legendary. Although I didn’t always agree with her quick acceptance of some sketchier evidence and fringier theories, I will gladly admit to “coming around” to numerous so-called “conspiracy theories” which she championed first. I was always careful to give her credit for being right, too, when I had been wrong.
It is impossible to overstate how much DePat did for not only this site, but for her country. I urge all to say a quick prayer of thanks, whenever you think of her, for the privilege of knowing, in life or after death, such an exemplary human being, and lover of God.
And thank you, Susie, for the firm foundation which you left us, when you were called to your true home!
Discussion of Authorship and Call for Authors
They say that crisis is opportunity, and they are right.
“Never let a crisis go to waste” – another saying, often attributed to the notorious Demoncrat thug, Rahm Emanuel.
We will pay attention to these adages, but we will try to be “nicer” about our small crisis.
Over the years (soon to be EIGHT on September 18, 2026), we have had authors come and go, especially on the seven “daily” open posts. At various times, some of our authors, like Deplorable Patriot, have handled more than one daily. DePat handled 1, 2, 3 and even 4 dailies (and we joked about giving her 5 – not entirely in jest!)
Right now, I am handling 3, and it feels fairly comfortable. Monday (Wheatie), Tuesday (DePat), and Thursday (Trust The Plan).
Gail, who does Wednesday, is dropping a few additional posts on Thursday, and it’s helpful to us both.
While I could probably just leave things as they are, I feel that it’s useful to give people the opportunity to try their hand at authoring posts here. We have had many pleasant surprises, as our readership has found both enlightenment and entertainment in new authors.
At one time, I would edit and post some articles written by Gail, but what I discovered at that time, is that it was not only too much work for both of us – it was causing me to be an editor again. I say again, because one of the many hats I’ve worn in this life, was that of an editor. I really, really do not like being an editor. I’m good at it, and received much money and approval for my efforts, but I hate it. When Gail finally began posting on her own, I said THANK YOU and NEVER AGAIN on the editing.
Thus, I have no desire to serve as an editor again, and that includes being an editor for those who would like to dip their toes into authorship by handing off articles. Nope. You have to be the person who types it in and hits either SAVE or PUBLISH.
If I open up opportunities for your authorship here, being classified in WordPress as an Author is your minimum contribution. You can produce nothing, or 4 dailies, or anything in between. But you must be your own author – not a shadow author. You will publish under your own username – nobody else’s – no “anonymous”. You can say whatever you want, but you will be responsible for what you say. If you need a more “anonymous” account than the one you already have, then we can work on that.
SO – please let me know if you are interested in being a weekly author on Monday, Tuesday, or Thursday. You can respond on this post, or by sending a “PMTW” message (see “Contact”).
If you have questions, fire away!
In the words of somebody we all love, “Thank you for your attention to this matter!”
This Stormwatch Monday Open Thread remains open – VERY OPEN – a place for everybody to post whatever they feel they would like to tell the White Hats, and the rest of the MAGA/KAG/KMAG world (with KMAG being a bit of both).
Our various sister sites, listed in the Blogroll in the sidebar
Our beloved country is STILL under DIRECT THREATS by hostile forces – notably COMMUNISTS – and they’re HERE IN AMERICA.
Daily outrage and commie phuckery still abound.
We can give in to despair…or we can be defiant and fight back in any way that we can.
Commies won’t win!
And we will keep saying COMMIES OUT until we get their FRAUD and INSANITY out of our country!
THE STUFF
Let This Be Counted as a House of the Lord
I call your attention to TWO pieces of scripture.
“Indeed, I count everything as loss because of the surpassing worth of knowing Christ Jesus my Lord.”
-Philippians 3:8
“Let us go to the house of the Lord!”
-Psalm 122:1
IMO this site has been providentially protected from harm by making sure – like a church – that there is no corner on this property in which there is the slightest hesitation in lifting the Lord’s name in praise, or a time when God cannot be worshipped.
Yes, we have a special service on Sunday, but I have noted that we have evolved to the point where there is no time or place in which anybody for any reason might hesitate to mention God or praise our Savior, Jesus of Nazareth.
Reading these two passages in rough sequence, and after several days of watching the failures of science surrounding money and vaccines, which failures and lies have no truck or traction here, I realized that together these pieces of scripture explain why our protection WORKS.
Christ Jesus was relentless in living the Ten Commandments, and demonstrating to us that this was not only possible for humans, but properly done, in love, it is a JOY, not a burden. Paul understood this – that ALL GOOD THINGS flow from a much more powerful thing – the abstraction of worshiping GOD over all else. Stated another way, that even Truth itself, and our choice to find it, rest upon a foundation created by God. Paul could never return the favor done to him by knowing what Christ taught him, but he could and did share that good news with all of humanity.
The same principle applies to this site. Let us BE a house of the Lord! What does that mean? It means that the surpassing value of what Christ taught us should cleanse every room, every hallway, every corridor, every nook and cranny, and even the BIN and the SPAM BUCKET.
At all times, remember. THIS is a House of the Lord. NEVER be afraid to speak His name. Post about God – comments or articles – whenever and wherever you desire. FEAR NOT. God is with us, because we make sure He is WELCOME.
This DePat Tuesday Open Thread honors the author of the original Tuesday open thread on this site, namely the late Susie Sampson, a.k.a. Deplorable Patriot, among her other handles, pen names, etc.
For more on the untimely passing of Dear DePat, please see these three posts.
At one time, DePat handled FOUR daily open threads here, in addition to taking care of her relatives, choir duties, and numerous other responsibilities. She was a powerhouse – a dynamo – a true force of nature.
DePat’s faith in Trump, Q, “The Plan”, the White Hats, and “the anons” in general, was legendary. Although I didn’t always agree with her quick acceptance of some sketchier evidence and fringier theories, I will gladly admit to “coming around” to numerous so-called “conspiracy theories” which she championed first. I was always careful to give her credit for being right, too, when I had been wrong.
It is impossible to overstate how much DePat did for not only this site, but for her country. I urge all to say a quick prayer of thanks, whenever you think of her, for the privilege of knowing, in life or after death, such an exemplary human being, and lover of God.
And thank you, Susie, for the firm foundation which you left us, when you were called to your true home!
The Myths and Realities of Human/Ape “Similarity” Numbers
If you have ever read or heard something about the genetic similarity of humans and (other) apes, and were suspicious of the numbers – whether you’re a fan or skeptic of evolution – then you were absolutely right to be suspicious.
This video, by an evolutionist who is something of an expert in the topic, will explain WHY you should be suspicious of genetic similarity numbers.
She is able to make this topic understandable, but unfortunately, it can get a bit boring, too. Grab some coffee and maybe some cookies.
The TL;DR is that there are an infinite number of ways to measure similarity, with completely different meanings, and every one has pluses and minuses. The worst thing – the thing that you can’t do – is mixing and matching different measurements. By one standard, 99.5% and 99.2% is a huge difference in similarities, but by a different one, 75% and 65% are almost the same, no big deal. By one standard, 99% similarity means it’s the same species at the same time. By another standard, 99% similarity could be two species that cannot interbreed, and one is a fossil.
Pretty meaningless, if you’re not extremely careful. The numbers change rapidly between methods, as you will see.
I am familiar with this problem, having designed similarity metrics for certain types of searched data at “Shallow State”. What one learns to do is to observe how the metric behaves, and interpret the results based on the metric, NOT based on what you think “100%”, “99%”, “95%”, “75%”, “50%”, and other values, should mean. If the metric works well for your purposes, that’s all you need. If it works perfectly for your most important cases, even better.
The numbers mean what THEY mean, not what YOU THINK they should mean. You will see this in spades, in the video.
Erika uses a “provocative question” about orangutans as a phony but effective way to get people to listen to an introductory lecture on similarity metrics in comparative genomics. If you listen all the way through, you get to hear her joke about this at the end. You also get to hear her excellent perspective about how massive the differences are between humans and (other) apes, in whatever percentage difference a particular metric gives.
And by then, you will be 100% skeptical of similarity numbers without explanation and context.
This Stormwatch Monday Open Thread remains open – VERY OPEN – a place for everybody to post whatever they feel they would like to tell the White Hats, and the rest of the MAGA/KAG/KMAG world (with KMAG being a bit of both).
There are Important Notifications from our host, Wolf Moon; the Rules of our late, good Wheatie; and, certain caveats from Yours Truly, of which readers should be aware. They are linked here. Note: Yours Truly has checked today’s post for any AI-generated content. To the best of her knowledge and belief, there is none. If readers wish to post any AI-generated content in the discussion thread for today’s post, they must cite their source. Thank you.
Do not forget to LABEL AI articles video and such.
I am going to leave Fauci’s Congressional hearing to PAVACA. She is much better equipped for that discussion.
Natalie Winters is one of the best ‘finds’ of Steve Bannon. POTUS has mentioned propaganda from China. I guess you can not get any more direct than this.
The names include:
– Ezra Klein, New York Times columnist – Matthew Yglesias, Vox co-founder – Ronald Brownstein, CNN senior political analyst – Bradford Plumer, New York Times reporter – Marjorie Miller, former Associated Press vice president
– Marilyn Geewax, former NPR senior editor – Kathleen Deveny, former Newsweek editor – Tom Omestad, former U.S. News & World Report correspondent – Steve Chapman, former Chicago Tribune columnist – Bruce Stokes, former National Journal correspondent
– Cristi Kempf, former Chicago Tribune associate managing editor – Jon Healey, Los Angeles Times deputy editorial page editor – Julian Pecquet, former Foreign Affairs reporter
I. Introduction – What Is American Strategy?……………..1
1. How American “Strategy” Went Astray…………………1
2. President Trump’s Necessary, Welcome Correction…… 2
II. What Should the United States Want?……………………… 3
1. What Do We Want Overall?………………………………………. 3
2. What Do We Want In and From the World?……………………..5
III. What Are America’s Available Means to Get What We Want?.. 6
IV. The Strategy………………………………………………………….8
1. Principles………………………………………………………………8
2. Priorities………………………………………………………….. 11
3. The Regions……………………………………………………….15
A. The Western Hemisphere……………………………………….15
B. Asia…………………………………………………………….. 19
C. Europe…………………………………………………………..25
D. The Middle East………………………………………………27
E. Africa………………………………………………………… 29
How American “Strategy” Went Astray
To ensure that America remains the world’s strongest, richest, most powerful, and most successful country for decades to come, our country needs a coherent, focused strategy for how we interact with the world… A “strategy” is a concrete, realistic plan that explains the essential connection between ends and means… A strategy must evaluate, sort, and prioritize. Not every country, region, issue, or cause—however worthy—can be the focus of American strategy…
…the affairs of other countries are our concern only if their activities directly threaten our interests.
The questions before us now are: 1) What should the United States want? 2) What are our available means to get it? and 3) How can we connect ends and means into a viable National Security Strategy?
II. What Should the United States Want?
1. What Do We Want Overall?
First and foremost, we want the continued survival and safety of the United States as an independent, sovereign republic whose government secures the God-given natural rights of its citizens and prioritizes their well-being and interests. We want to protect this country, its people, its territory, its economy, and its way of life…
We want to recruit, train, equip, and field the world’s most powerful, lethal, and technologically advanced military to protect our interests, deter wars, and—if necessary—win them quickly and decisively, with the lowest possible casualties to our forces…. We want the world’s strongest, most dynamic, most innovative, and most advanced economy. The U.S. economy is the bedrock of the American way of life, which promises and delivers widespread and broad-based prosperity…
Cultivating American industrial strength must become the highest priority of national economic policy.
We want the world’s most robust, productive, and innovative energy sector—one capable not just of fueling American economic growth but of being one of America’s leading export industries in its own right. We want to remain the world’s most scientifically and technologically advanced and innovative country, and to build on these strengths. And we want to protect our intellectual property from foreign theft. America’s pioneering spirit is a key pillar of our continued economic dominance and military superiority; it must be preserved… Finally, we want the restoration and reinvigoration of American spiritual and cultural health, without which long-term security is impossible…
2. What Do We Want In and From the World?
• We want to ensure that the Western Hemisphere remains reasonably stable and well-governed enough to prevent and discourage mass migration to the United States…
• We want to halt and reverse the ongoing damage that foreign actors inflict on the American economy…
• We want to support our allies in preserving the freedom and security of Europe, while restoring Europe’s civilizational self-confidence and Western identity
• We want to prevent an adversarial power from dominating the Middle East…
• We want to ensure that U.S. technology and U.S. standards—particularly in AI, biotech, and quantum computing—drive the world forward.
These are the United States’ core, vital national interests. While we also have others, these are the interests we must focus on above all others, and that we ignore or neglect at our peril.
III. What Are America’s Available Means to Get What We Want?
America retains the world’s most enviable position, with world-leading assets, resources, and advantages, including:
…The world’s single largest and most innovative economy, which both generates wealth we can invest in strategic interests and provides leverage over countries that want access to our markets… The world’s most advanced, most innovative, and most profitable technology sector… An enviable geography with abundant natural resources, no competing powers physically dominant in our Hemisphere, borders at no risk of military invasion, and other great powers separated by vast oceans;..
In addition, through President Trump’s robust domestic agenda, the United States is:
• Re-instilling a culture of competence, rooting out so-called “DEI” and other discriminatory and anti-competitive practices that degrade our institutions and hold us back;
• Unleashing our enormous energy production capacity as a strategic priority to fuel growth and innovation, and to bolster and rebuild the middle class;
• Reindustrializing our economy, again to further support the middle class and control our own supply chains and production capacities;
• Returning economic freedom to our citizens via historic tax cuts and deregulatory efforts, making the United States the premier place to do business and invest capital; and
• Investing in emerging technologies and basic science, to ensure our continued prosperity, competitive advantage, and military dominance for future generations.
The goal of this strategy is to tie together all of these world-leading assets, and others, to strengthen American power and preeminence and make our country even greater than it ever has been…. [Ending at pg 11 in the PDF, page 7 in the document.]
Skip down to page 24 in the PDF page 20 in the document.
Economics: The Ultimate Stakes
Since the Chinese economy reopened to the world in 1979, commercial relations between our two countries have been and remain fundamentally unbalanced. What began as a relationship between a mature, wealthy economy and one of the world’s poorest countries has transformed into one between near-peers, even as, until very recently, America’s posture remained rooted in those past assumptions.
China adapted to the shift in U.S. tariff policy that began in 2017 in part by strengthening its hold on supply chains, especially in the world’s low- and middleincome (i.e., per capita GDP $13,800 or less) countries—among the greatest economic battlegrounds of the coming decades…
To accomplish this, several things are essential.
First, the United States must protect and defend our economy and our people from harm, from any country or source. This means ending (among other things): • Predatory, state-directed subsidies and industrial strategies; • Unfair trading practices; • Job destruction and deindustrialization; • Grand-scale intellectual property theft and industrial espionage; • Threats against our supply chains that risk U.S. access to critical resources, including minerals and rare earth elements; • Exports of fentanyl precursors that fuel America’s opioid epidemic; and • Propaganda, influence operations, and other forms of cultural subversion. Second, the United States must work with our treaty allies and partners—who together add another $35 trillion in economic power to our own $30 trillion national economy (together constituting more than half the world economy)—to counteract predatory economic practices and use our combined economic power to help safeguard our prime position in the world economy and ensure that allied economies do not become subordinate to any competing power. We must continue to improve commercial (and other) relations with India to encourage New Delhi to contribute to Indo-Pacific security, including through continued quadrilateral cooperation with Australia, Japan, and the United States (“the Quad”). Moreover, we will also work to align the actions of our allies and partners with our joint interest in preventing domination by any single competitor nation.
The United States must at the same time invest in research to preserve and advance our advantage in cutting-edge military and dual-use technology, with emphasis on the domains where U.S. advantages are strongest. These include undersea, space, and nuclear, as well as others that will decide the future of military power, such as AI, quantum computing, and autonomous systems, plus the energy necessary to fuel these domains. Additionally, the U.S. Government’s critical relationships with the American private sector help maintain surveillance of persistent threats to U.S. networks, including critical infrastructure. This in turn enables the U.S. Government’s ability to conduct real-time discovery, attribution, and response…
Section 1. Purpose. From the founding of our Republic, scientific discovery and technological innovation have driven American progress and prosperity. Today, America is in a race for global technology dominance in the development of artificial intelligence (AI), an important frontier of scientific discovery and economic growth. To that end, my Administration has taken a number of actions to win that race, including issuing multiple Executive Orders and implementing America’s AI Action Plan, which recognizes the need to invest in AI-enabled science to accelerate scientific advancement. In this pivotal moment, the challenges we face require a historic national effort, comparable in urgency and ambition to the Manhattan Project that was instrumental to our victory in World War II and was a critical basis for the foundation of the Department of Energy (DOE) and its national laboratories.
This order launches the “Genesis Mission” as a dedicated, coordinated national effort to unleash a new age of AI‑accelerated innovation and discovery that can solve the most challenging problems of this century. The Genesis Mission will build an integrated AI platform to harness Federal scientific datasets — the world’s largest collection of such datasets, developed over decades of Federal investments — to train scientific foundation models and create AI agents to test new hypotheses, automate research workflows, and accelerate scientific breakthroughs. The Genesis Mission will bring together our Nation’s research and development resources — combining the efforts of brilliant American scientists, including those at our national laboratories, with pioneering American businesses; world-renowned universities; and existing research infrastructure, data repositories, production plants, and national security sites — to achieve dramatic acceleration in AI development and utilization. We will harness for the benefit of our Nation the revolution underway in computing, and build on decades of innovation in semiconductors and high-performance computing. The Genesis Mission will dramatically accelerate scientific discovery, strengthen national security, secure energy dominance, enhance workforce productivity, and multiply the return on taxpayer investment into research and development, thereby furthering America’s technological dominance and global strategic leadership.
Sec. 2. Establishment of the Genesis Mission. (a) There is hereby established the Genesis Mission (Mission), a national effort to accelerate the application of AI for transformative scientific discovery focused on pressing national challenges.
(b) The Secretary of Energy (Secretary) shall be responsible for implementing the Mission
Sec. 3. Operation of the American Science and Security Platform. (a) The Secretary shall establish and operate the American Science and Security Platform (Platform) to serve as the infrastructure for the Mission with the purpose of providing, in an integrated manner and to the maximum extent practicable and consistent with law:
(i) high-performance computing resources, including DOE national laboratory supercomputers and secure cloud-based AI computing environments, capable of supporting large-scale model training, simulation, and inference;
(ii) AI modeling and analysis frameworks, including AI agents to explore design spaces, evaluate experimental outcomes, and automate workflows;
(iii) computational tools, including AI-enabled predictive models, simulation models, and design optimization tools;
(iv) domain-specific foundation models across the range of scientific domains covered;
(v) secure access to appropriate datasets, including proprietary, federally curated, and open scientific datasets, in addition to synthetic data generated through DOE computing resources, consistent with applicable law; applicable classification, privacy, and intellectual property protections; and Federal data-access and data-management standards; and
(vi) experimental and production tools to enable autonomous and AI-augmented experimentation and manufacturing in high-impact domains.
(b) The Secretary shall take necessary steps to ensure that the Platform is operated in a manner that meets security requirements consistent with its national security and competitiveness mission, including applicable classification, supply chain security, and Federal cybersecurity standards and best practices…
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For those of us following the destruction of science over the past decades:
Section 1. Policy and Purpose. Over the last 5 years, confidence that scientists act in the best interests of the public has fallen significantly. A majority of researchers in science, technology, engineering, and mathematics believe science is facing a reproducibility crisis. The falsification of data by leading researchers has led to high-profile retractions of federally funded research.
Unfortunately, the Federal Government has contributed to this loss of trust. In several notable cases, executive departments and agencies (agencies) have used or promoted scientific information in a highly misleading manner…
Sec. 2. Definitions….
Sec. 3. Restoring Gold Standard Science. (a) Within 30 days of the date of this order, the Director of the Office of Science and Technology Policy (OSTP Director) shall, in consultation with the heads of relevant agencies, issue guidance for agencies on implementation of “Gold Standard Science” in the conduct and management of their respective scientific activities. For the purposes of this order, Gold Standard Science means science conducted in a manner that is: (i) reproducible; (ii) transparent; (iii) communicative of error and uncertainty; (iv) collaborative and interdisciplinary; (v) skeptical of its findings and assumptions; (vi) structured for falsifiability of hypotheses; (vii) subject to unbiased peer review; (viii) accepting of negative results as positive outcomes; and (ix) without conflicts of interest.
Sec. 4. Improving the Use, Interpretation, and Communication of Scientific Data…
Sec. 5. Interim Scientific Integrity Policies. (a) Until the issuance of updated agency scientific integrity policies pursuant to section 3 of this order, and except where required by law: (i) scientific integrity policies in each agency shall be governed by the scientific integrity policies that existed within the executive branch on January 19, 2021, except that in the event of a conflict between such policies and the policies and requirements of this order, the policies and requirements of this order control…
Sec. 6. Scope and Applicability. (a) The policies and rules set forth in this order apply to all employees involved in the generation, use, interpretation, or communication of scientific information, regardless of job classification, and to all agency decision-making, except where precluded by law…
Section 1. Purpose. Artificial intelligence (AI) will play a critical role in how Americans of all ages learn new skills, consume information, and navigate their daily lives. Americans will require reliable outputs from AI, but when ideological biases or social agendas are built into AI models, they can distort the quality and accuracy of the output.
One of the most pervasive and destructive of these ideologies is so-called “diversity, equity, and inclusion” (DEI). In the AI context, DEI includes the suppression or distortion of factual information about race or sex; manipulation of racial or sexual representation in model outputs; incorporation of concepts like critical race theory, transgenderism, unconscious bias, intersectionality, and systemic racism; and discrimination on the basis of race or sex. DEI displaces the commitment to truth in favor of preferred outcomes and, as recent history illustrates, poses an existential threat to reliable AI…